Mucoepidermoid carcinoma surgery: Difference between revisions
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{{Mucoepidermoid carcinoma}} | {{Mucoepidermoid carcinoma}} | ||
{{CMG}} | {{CMG}}{{AE}}{{Badria}} , {{MV}} | ||
==Overview== | ==Overview== | ||
Surgery is the mainstay of therapy for mucoepidermoid carcinoma. | |||
==Surgery== | |||
*Mucoepidermoid carcinoma (low-grade): complete surgical excision with sparing of the facial nerve.<ref name="ppp">Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016</ref><ref name="ppp">Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016</ref> | |||
*Mucoepidermoid carcinoma (high-grade): [[parotidectomy]] with [[facial nerve]] sparing may be followed by [[radiotherapy]]. | |||
*Clinically aggressive mucoepidermoid carcinoma tumors with [[facial nerve]] involvement will require radical surgery with sacrifice of the [[facial nerve]] and [[radiotherapy]]. <ref name="pmid29318070">{{cite journal |vauthors=Gedar Totuk OM, Demir MK, Yapicier O, Mestanoglu M |title=Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient |journal=Case Rep Ophthalmol Med |volume=2017 |issue= |pages=2418505 |date=2017 |pmid=29318070 |pmc=5727657 |doi=10.1155/2017/2418505 |url=}}</ref> | |||
*Primary nerve grafting using the [[sural nerve]] if possible is performed. | |||
*[[Lymph node]] dissection is usually only performed for detected nodal metastasis. | |||
* Low grade mucoepidermoid carcinoma in the floor of the mouth can be surgically excised along with involved [[lymph node]].<ref name="pmid14662408">{{cite journal |vauthors=Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A |title=Management of malignant sublingual salivary gland tumors |journal=Oral Oncol. |volume=40 |issue=1 |pages=2–5 |date=January 2004 |pmid=14662408 |doi= |url=}}</ref><ref name="pmid9261001">{{cite journal |vauthors=Helmus C |title=Subtotal parotidectomy: a 10-year review (1985 to 1994) |journal=Laryngoscope |volume=107 |issue=8 |pages=1024–7 |date=August 1997 |pmid=9261001 |doi= |url=}}</ref> | |||
* When the tumor is at an inaccessible location, clinical trial therapies (especially for stage IV disease) including: | |||
** Therapeutic drugs | |||
** Radiation | |||
** Stem cell transplantation | |||
** Monoclonal antibodies | |||
* Either singly or in combination of various therapies | |||
* Follow-up care with regular screening and check-ups are important<ref name="pmid26813873">{{cite journal |vauthors=Maloth AK, Nandan SR, Kulkarni PG, Dorankula SP, Muddana K |title=Mucoepidermoid Carcinoma of Floor of the Mouth - A Rarity |journal=J Clin Diagn Res |volume=9 |issue=12 |pages=ZD03–4 |date=December 2015 |pmid=26813873 |pmc=4717804 |doi=10.7860/JCDR/2015/15595.6912 |url=}}</ref> | |||
==Indications== | |||
*Indications for surgery for mucoepidermoid carcinoma, include:<ref name="RapidisGivalos2007">{{cite journal|last1=Rapidis|first1=Alexander D.|last2=Givalos|first2=Nikolaos|last3=Gakiopoulou|first3=Hariklia|last4=Stavrianos|first4=Spyros D.|last5=Faratzis|first5=Gregory|last6=Lagogiannis|first6=George A.|last7=Katsilieris|first7=Ioannis|last8=Patsouris|first8=Efstratios|title=Mucoepidermoid carcinoma of the salivary glands.|journal=Oral Oncology|volume=43|issue=2|year=2007|pages=130–136|issn=13688375|doi=10.1016/j.oraloncology.2006.03.001}}</ref> | |||
:*Biological and histological features suitable for surgery | |||
==Gallery== | |||
{{#ev:youtube|20sj0dJI6Xg}} | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Oral pathology]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Medicine]] | |||
[[Category: | [[Category:Otolaryngology]] | ||
Latest revision as of 19:49, 22 January 2019
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Mucoepidermoid carcinoma Microchapters |
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Differentiating Mucoepidermoid Carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Mucoepidermoid carcinoma surgery On the Web |
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American Roentgen Ray Society Images of Mucoepidermoid carcinoma surgery |
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Risk calculators and risk factors for Mucoepidermoid carcinoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Badria Munir M.B.B.S.[2] , Maria Fernanda Villarreal, M.D. [3]
Overview
Surgery is the mainstay of therapy for mucoepidermoid carcinoma.
Surgery
- Mucoepidermoid carcinoma (low-grade): complete surgical excision with sparing of the facial nerve.[1][1]
- Mucoepidermoid carcinoma (high-grade): parotidectomy with facial nerve sparing may be followed by radiotherapy.
- Clinically aggressive mucoepidermoid carcinoma tumors with facial nerve involvement will require radical surgery with sacrifice of the facial nerve and radiotherapy. [2]
- Primary nerve grafting using the sural nerve if possible is performed.
- Lymph node dissection is usually only performed for detected nodal metastasis.
- Low grade mucoepidermoid carcinoma in the floor of the mouth can be surgically excised along with involved lymph node.[3][4]
- When the tumor is at an inaccessible location, clinical trial therapies (especially for stage IV disease) including:
- Therapeutic drugs
- Radiation
- Stem cell transplantation
- Monoclonal antibodies
- Either singly or in combination of various therapies
- Follow-up care with regular screening and check-ups are important[5]
Indications
- Indications for surgery for mucoepidermoid carcinoma, include:[6]
- Biological and histological features suitable for surgery
Gallery
{{#ev:youtube|20sj0dJI6Xg}}
References
- ↑ 1.0 1.1 Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016
- ↑ Gedar Totuk OM, Demir MK, Yapicier O, Mestanoglu M (2017). "Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient". Case Rep Ophthalmol Med. 2017: 2418505. doi:10.1155/2017/2418505. PMC 5727657. PMID 29318070.
- ↑ Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A (January 2004). "Management of malignant sublingual salivary gland tumors". Oral Oncol. 40 (1): 2–5. PMID 14662408.
- ↑ Helmus C (August 1997). "Subtotal parotidectomy: a 10-year review (1985 to 1994)". Laryngoscope. 107 (8): 1024–7. PMID 9261001.
- ↑ Maloth AK, Nandan SR, Kulkarni PG, Dorankula SP, Muddana K (December 2015). "Mucoepidermoid Carcinoma of Floor of the Mouth - A Rarity". J Clin Diagn Res. 9 (12): ZD03–4. doi:10.7860/JCDR/2015/15595.6912. PMC 4717804. PMID 26813873.
- ↑ Rapidis, Alexander D.; Givalos, Nikolaos; Gakiopoulou, Hariklia; Stavrianos, Spyros D.; Faratzis, Gregory; Lagogiannis, George A.; Katsilieris, Ioannis; Patsouris, Efstratios (2007). "Mucoepidermoid carcinoma of the salivary glands". Oral Oncology. 43 (2): 130–136. doi:10.1016/j.oraloncology.2006.03.001. ISSN 1368-8375.