Mepolizumab: Difference between revisions

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List of terms related to Mepolizumab

Mepolizumab
Monoclonal antibody
Type	Whole antibody
Source	Template:Infobox drug/mab source
Target	IL-5
Clinical data
ATC code	L04AC06 (WHO) ;
Pharmacokinetic data
Elimination half-life	20 days
Identifiers
CAS Number	196078-29-2 ;
ChemSpider	NA ;
KEGG	D04923 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
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VisualWikitext

Revision as of 14:42, 9 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mepolizumab is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5). Mepolizumab has been investigated or is under investigation for the treatment of severe eosinophilic asthma, atopic dermatitis, hypereosinophilic syndrome (HES), eosinophilic esophagitis (EoE), nasal polyposis, eosinophilic granulomatosis with polyangiitis (EGPA) (i.e., Churg Strauss syndrome), and chronic obstructive pulmonary disease (COPD). Phase III clinical trials in severe eosinophilic asthma were completed in 2014.

@@ Line 1: / Line 1: @@
-{{drugbox-mab
+{{Drugbox
+| Verifiedfields = changed
+| verifiedrevid = 462248575
 | image =
-| source = [[Human]]
+<!--Monoclonal antibody data-->
+| type = mab
+| mab_type = mab
+| source = zu/o
 | target = [[Interleukin 5|IL-5]]
-| CAS_number =
-| ATC_prefix =
+<!--Clinical data-->
-| ATC_suffix =
+| tradename =
-| PubChem =
+| pregnancy_AU =
-| DrugBank =
+| pregnancy_US =
-| chemical_formula =
-| molecular_weight =
-| bioavailability =
-| protein_bound =
-| metabolism =
-| elimination_half-life =
-| excretion =
-| pregnancy_AU =
-| pregnancy_US =
 | pregnancy_category =
 | legal_AU =
 | legal_CA =
 | legal_UK =
 | legal_US =
 | legal_status =
 | routes_of_administration =
-}}
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life = 20 days
+| excretion =
-'''Mepolizumab''' is a [[human]] [[monoclonal antibody]], used as an [[immunosuppressive drug]] used to treat [[Hypereosinophilic Syndrome]].
+<!--Identifiers-->
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = NA
+| CAS_number_Ref = {{cascite|changed|??}}
+| CAS_number = 196078-29-2
+| ATC_prefix = L04
+| ATC_suffix = AC06
+| PubChem =
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D04923
-{{immunosuppressants}}
+<!--Chemical data-->
-{{humanizedmonoclonals}}
+| chemical_formula =
-[[Category:Monoclonal antibodies]]
+| molecular_weight =
+}}
+__Notoc__
+{{SI}}
+{{CMG}}
+==Overview==
+'''Mepolizumab'''  is a [[humanized antibody|humanized]] [[monoclonal antibody]] that recognizes [[interleukin-5]] (IL-5).
+Mepolizumab has been investigated or is under investigation for the treatment of severe eosinophilic [[asthma]], [[atopic dermatitis]], [[hypereosinophilic syndrome]] (HES), [[eosinophilic esophagitis]] (EoE), [[nasal polyposis]], [[eosinophilic granulomatosis with polyangiitis]] (EGPA) (i.e., Churg Strauss syndrome), and [[chronic obstructive pulmonary disease]] (COPD). Phase III clinical trials in severe eosinophilic asthma were completed in 2014.
-{{monoclonal-antibody-stub}}
+[[Category:Drug]]
-{{WikiDoc Sources}}
+[[Category:Monoclonal antibodies]]

Mepolizumab: Difference between revisions

Revision as of 14:42, 9 April 2015

Overview

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