Iohexol

Iohexol

File:Iohexol.svg
Clinical data
Pregnancy category	US: B (No risk in non-human studies)
Routes of administration	Intrathecal, intravascular, oral, intracavital
ATC code	V08AB02 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding	Low
Metabolism	Nil
Elimination half-life	Variable
Excretion	Renal, unchanged
Identifiers
IUPAC name 5-(acetyl-(2,3-dihydroxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodo-benzene-1,3- dicarboxamide
CAS Number	66108-95-0
PubChem CID	3730
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H26I3N3O9
Molar mass	821.138 g/mol
3D model (JSmol)	Interactive image
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.

The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.

External links

• Omnipaque (Iohexol) injection, solution

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