Diatrizoic acid

Diatrizoic acid
File:DiatrizoicAcid.PNG
IUPAC name	3,5-diacetamido-2,4,6-triiodo-benzoic acid
Identifiers
CAS number
SMILES	CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I
Properties
Molecular formula	C11H9I3N2O4
Molar mass	613.9 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Diatrizoic acid (or its anionic form, Diatrizoate), also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is an iodine-containing radiocontrast agent. It is also used to kill tapeworms.

Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution) to over 2000 mOsm/kg (76% solution).

Administration

• It is given intravenously (under brand name Hypaque®, GE Healthcare) to enhance contrast in computed tomography, to image the kidneys and related structures, and to image blood vessels.
• It is given orally or by enema (Gastrografin®, Gastrovist®, Gastrovision®, MD-Gastroview®) to image the gastrointestinal tract.
• It is given by Foley catheter (Cystografin®) to image the urinary tract

Contraindications

A history of sensitivity to iodine is not a contraindication to using diatrizoate, although it suggests caution in use of the agent.