Insulinoma (patient information): Difference between revisions

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{{Infobox_Disease |
{{Infobox_Disease |
   Name          = {{PAGENAME}} |
   Name          = {{PAGENAME}} |
  Image          = Pancreatic insulinoma (2).jpg |
  Caption        = Histopathology of pancreatic endocrine tumor (insulinoma). |
   DiseasesDB    = 6830 |
   DiseasesDB    = 6830 |
   ICD10          = {{ICD10|C|25|4|c|15}}, {{ICD10|D|13|7|d|10}} |
   ICD10          = {{ICD10|C|25|4|c|15}}, {{ICD10|D|13|7|d|10}} |
Line 11: Line 9:
   OMIM          = |
   OMIM          = |
   MedlinePlus    = |
   MedlinePlus    = |
  eMedicineSubj  = med |
  eMedicineTopic = 2677 |
   MeshID        = D007340 |
   MeshID        = D007340 |
}}
}}
{{SI}}
{{SI}}
{{CMG}}; Jinhui Wu, MD
'''Editor-in-Chief:''' [[C. Michael Gibson]], M.S.,M.D. [mailto:mgibson@perfuse.org]  Phone:617-632-7753; '''Associate Editor-In-Chief:''' Jinhui Wu, M.D.


{{EJ}}
==Overview==
 
==What is insulinoma?==
An insulinoma is a benign tumor in the pancreas which is an organ in the abdomen that can make insulin to regulate blood sugar level. A patient of insulinoma can produce too much insulin. Patients may show a series of symptoms of hypoglycemia, such as anxiety, behavior changes, confusion, dizziness, headache and hunger. Treatments invlove surgery and medication.
An insulinoma is a benign tumor in the pancreas which is an organ in the abdomen that can make insulin to regulate blood sugar level. A patient of insulinoma can produce too much insulin. Patients may show a series of symptoms of hypoglycemia, such as anxiety, behavior changes, confusion, dizziness, headache and hunger. Treatments invlove surgery and medication.


==How do I know if I have insulinoma and what are the symptoms of insulinoma?==
==What are the symptoms of insulinoma?==
Usual symptoms of insulinoma invlove a series of signs of hypoglycemia and other things:
Usual symptoms of insulinoma invlove a series of signs of hypoglycemia and other things:


:*[[Hunger]]
*[[Hunger]]


:*[[Sweating]]
*[[Sweating]]


:*[[Palpitation]]
*[[Palpitation]]


:*[[Anxiety]]
*[[Anxiety]]


:*[[Behavior changes]]
*[[Behavior changes]]


:*[[Clouded vision]]
*[[Clouded vision]]


:*[[Convulsions]]
*[[Convulsions]]


:*[[Dizziness]]
*[[Dizziness]]


:*[[Headache]]
*[[Headache]]


:*[[Confusion]], even [[loss of consciousness]]
*[[Confusion]], even [[loss of consciousness]]
   
   
:*[[Tremor]]
*[[Tremor]]


:*[[Weight gain]]
*[[Weight gain]]


Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.
Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.
Line 57: Line 50:


==How to know you have insulinoma?==
==How to know you have insulinoma?==
:*Blood tests: The patient needs to test the blood level of glucose, insulin and [[C-peptide]], when suspected to diagnose insulinoma.
*'''Blood tests:''' The patient needs to test the blood level of glucose, insulin and [[C-peptide]], when suspected to diagnose insulinoma.
:*Insulin suppression tests: This test is done to see whether insulin levels fail to suppress, which is a strong indicator of the presence of an insulin-secreting tumour.  
*'''Insulin suppression tests:''' This test is done to see whether insulin levels fail to suppress, which is a strong indicator of the presence of an insulin-secreting tumour.  
:*[[Computed tomography]] ([[CT]]) scan: CT scans are often used to diagnose insulinoma. It can confirm the location of the tumor and show the organs near the [[pancreas]].  
*'''[[Computed tomography]] ([[CT]]) scan:''' CT scans are often used to diagnose insulinoma. It can confirm the location of the tumor and show the organs near the [[pancreas]].  
:*[[Magnetic resonance imaging]] ([[MRI]]): An [[MRI]] uses magnetic fields but it is a different type of image than what is produced by computed tomography (CT) and produces detailed images of the body. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture.
*'''[[Magnetic resonance imaging]] ([[MRI]]):''' An [[MRI]] uses magnetic fields but it is a different type of image than what is produced by computed tomography (CT) and produces detailed images of the body. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture.


==When to seek urgent medical care?==
==When to seek urgent medical care?==
Call your health care provider if symptoms of insulinoma develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:  
Call your health care provider if symptoms of insulinoma develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:  


:*[[Convulsions]]
*[[Convulsions]]


:*[[Confusion]], even [[loss of consciousness]]
*[[Confusion]],  
 
*Even [[loss of consciousness]]


==Treatment options==
==Treatment options==
For patients with insulinoma, surgery is the definitive management. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities.  
For patients with insulinoma, surgery is the definitive management. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities.  


:*Surgery: The surgical measure may involve surgical removal of the insulinoma and removing part of the pancreas such as Whipple procedure and distal pancreatectomy.
*Surgery: The surgical measure may involve surgical removal of the insulinoma and removing part of the pancreas such as Whipple procedure and distal pancreatectomy.


:*Medication: For patients who may not accept surgery, medications such as diazoxide and somatostatin can be used to block the release of insulin.
*Medication: For patients who may not accept surgery, medications such as diazoxide and somatostatin can be used to block the release of insulin.


==Diseases with similar symptoms==
==Diseases with similar symptoms==
:*[[Hypoglycemia]] by other causes
*[[Hypoglycemia]] by other causes


:*[[Seizures]]
*[[Seizures]]


:*[[Stroke]]
*[[Stroke]]


:*[[Schizophrenia]] or [[hysteria]]
*[[Schizophrenia]] or [[hysteria]]


==Where to find medical care for insulinoma?==
==Where to find medical care for insulinoma?==
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As a kind of benign tumor, the prognosis of insulinoma is good. Surgery can cure most patients. But a severe hypoglycemic reaction may be life-threatening for some patients.
As a kind of benign tumor, the prognosis of insulinoma is good. Surgery can cure most patients. But a severe hypoglycemic reaction may be life-threatening for some patients.


==Copyleft Sources==
==Sources==
http://www.nlm.nih.gov/medlineplus/ency/article/000387.htm
http://www.nlm.nih.gov/medlineplus/ency/article/000387.htm
{{{SIB}}
[[Category:Disease state]]
[[Category:Endocrinology]]
[[Category:Oncology]]
[[Category:Patient information]]
[[Category:Endocrinology patient information]]
[[Category:Oncology patient information]]
[[Category:Mature chapter]]


{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category:Patient Information]]

Revision as of 23:23, 28 July 2011

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Insulinoma (patient information)
ICD-10 C25.4, D13.7
ICD-9 157.4, 211.7
ICD-O: 8151
DiseasesDB 6830
MeSH D007340

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Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor-In-Chief: Jinhui Wu, M.D.

Overview

An insulinoma is a benign tumor in the pancreas which is an organ in the abdomen that can make insulin to regulate blood sugar level. A patient of insulinoma can produce too much insulin. Patients may show a series of symptoms of hypoglycemia, such as anxiety, behavior changes, confusion, dizziness, headache and hunger. Treatments invlove surgery and medication.

What are the symptoms of insulinoma?

Usual symptoms of insulinoma invlove a series of signs of hypoglycemia and other things:

Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.

Who is at risk for insulinoma?

The cause of insulinoma is not clear.

How to know you have insulinoma?

  • Blood tests: The patient needs to test the blood level of glucose, insulin and C-peptide, when suspected to diagnose insulinoma.
  • Insulin suppression tests: This test is done to see whether insulin levels fail to suppress, which is a strong indicator of the presence of an insulin-secreting tumour.
  • Computed tomography (CT) scan: CT scans are often used to diagnose insulinoma. It can confirm the location of the tumor and show the organs near the pancreas.
  • Magnetic resonance imaging (MRI): An MRI uses magnetic fields but it is a different type of image than what is produced by computed tomography (CT) and produces detailed images of the body. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture.

When to seek urgent medical care?

Call your health care provider if symptoms of insulinoma develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:

Treatment options

For patients with insulinoma, surgery is the definitive management. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities.

  • Surgery: The surgical measure may involve surgical removal of the insulinoma and removing part of the pancreas such as Whipple procedure and distal pancreatectomy.
  • Medication: For patients who may not accept surgery, medications such as diazoxide and somatostatin can be used to block the release of insulin.

Diseases with similar symptoms

Where to find medical care for insulinoma?

Directions to Hospitals Treating insulinoma

Prevention of insulinoma

For the cause is not clear, there is no known method for prevention.

What to expect (Outook/Prognosis)?

As a kind of benign tumor, the prognosis of insulinoma is good. Surgery can cure most patients. But a severe hypoglycemic reaction may be life-threatening for some patients.

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000387.htm

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