Immunoglobulin D
WikiDoc Resources for Immunoglobulin D |
Articles |
---|
Most recent articles on Immunoglobulin D Most cited articles on Immunoglobulin D |
Media |
Powerpoint slides on Immunoglobulin D |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Immunoglobulin D at Clinical Trials.gov Trial results on Immunoglobulin D Clinical Trials on Immunoglobulin D at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Immunoglobulin D NICE Guidance on Immunoglobulin D
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Immunoglobulin D Discussion groups on Immunoglobulin D Patient Handouts on Immunoglobulin D Directions to Hospitals Treating Immunoglobulin D Risk calculators and risk factors for Immunoglobulin D
|
Healthcare Provider Resources |
Causes & Risk Factors for Immunoglobulin D |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually coexpressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found in very small amounts in blood serum. Secreted IgD is produced as a monomeric antibody with two heavy chains of the delta (δ) class, and two Ig light chains.
Function
IgD's function is currently unknown, as mice lacking IgD seem to retain normal immune responses (implying redundancy if not lack of function), and IgD ceases to be expressed in activated B-lymphocytes. It may function as a regulatory antigen receptor.
See also
External links
- Immunoglobulin+D at the US National Library of Medicine Medical Subject Headings (MeSH)