Hypoglycemia echocardiography or ultrasound: Difference between revisions

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{{Hypoglycemia}}
{{Hypoglycemia}}
{{CMG}} {{AE}} {{MAD}}
{{CMG}} {{AE}} {{ADS}} {{MAD}}
==Overview==
==Overview==
Transabdominal ultrasound has low sensitivity varying between 0-66% in detecting insulinoma. The sensitivity increases with the use of more invasive endoscopic ultrasound (93%) and intraoperative ultrasound (86%).We see hypoechoic lesions and hypervascular mass on the ultrasound.
[[Ultrasound|Transabdominal ultrasound]] has low [[sensitivity]] varying between 0-66% in detecting [[insulinoma]]. The sensitivity increases with the use of more invasive [[endoscopic ultrasound]] (93%) and intraoperative ultrasound (86%). Hypoechoic lesion and hypervascular mass are ultrasonographic findings.


== Transabdominal Ultrasound==
== Transabdominal Ultrasound==


*Ultrasound may be helpful in the diagnosis of [[insulinoma]]. The senstivity varies from 0-66%. Smaller tumor are difficult to detect especially those on pancreas tail. Findings on a transabdominal [[ultrasound]] suggestive of insulinoma include<ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref>:
*Ultrasound may be helpful in the diagnosis of [[insulinoma]]. The sensitivity varies from 0-66%. The smaller tumor is difficult to detect especially those on [[pancreas]] tail. Findings on a transabdominal [[ultrasound]] suggestive of [[insulinoma]] include<ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref>:
** Low [[echogenicity]]
** Low [[echogenicity]]
** Hypervascularity on the [[Doppler ultrasound|Doppler]]
** Hypervascularity on the [[Doppler ultrasound|Doppler]]


*An ultrasound may be helpful in the diagnosis of complications of [[malignant]] insulinoma, which include:
*An [[ultrasound]] may be helpful in the diagnosis of complications of [[malignant]] [[insulinoma]], which include liver [[metastasis]].
**liver [[metastasis]]


==Invasive Ultrasound==
==Invasive Ultrasound==
===Endoscopic Ultrasound===
===Endoscopic Ultrasound===
This is an invasive ultrasound which can be done pre-operatively. The use has been increased with the increase in senstivities from 40-93%, more accurate in pancreatic head insulinomas. It is supported as the primary diagnostic modality for the diagnosis of pancreatic neuroendocrine tumors (which includes insulinoma) <ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref>
This is an invasive [[ultrasound]] which can be done pre-operatively. Its use has been increased with improve in its sensitivity. Endoscopic ultrasound is more accurate for pancreatic head [[Insulinoma|insulinomas.]] It is the primary diagnostic modality for the diagnosis of pancreatic [[neuroendocrine tumors]] (which includes [[insulinoma]]).<ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref><ref name="pmid17906369">{{cite journal| author=Sotoudehmanesh R, Hedayat A, Shirazian N, Shahraeeni S, Ainechi S, Zeinali F et al.| title=Endoscopic ultrasonography (EUS) in the localization of insulinoma. | journal=Endocrine | year= 2007 | volume= 31 | issue= 3 | pages= 238-41 | pmid=17906369 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17906369  }} </ref><ref name="pmid11007228">{{cite journal| author=Anderson MA, Carpenter S, Thompson NW, Nostrant TT, Elta GH, Scheiman JM| title=Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas. | journal=Am J Gastroenterol | year= 2000 | volume= 95 | issue= 9 | pages= 2271-7 | pmid=11007228 | doi=10.1111/j.1572-0241.2000.02480.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11007228  }} </ref>
<ref name="pmid17906369">{{cite journal| author=Sotoudehmanesh R, Hedayat A, Shirazian N, Shahraeeni S, Ainechi S, Zeinali F et al.| title=Endoscopic ultrasonography (EUS) in the localization of insulinoma. | journal=Endocrine | year= 2007 | volume= 31 | issue= 3 | pages= 238-41 | pmid=17906369 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17906369  }} </ref><ref name="pmid11007228">{{cite journal| author=Anderson MA, Carpenter S, Thompson NW, Nostrant TT, Elta GH, Scheiman JM| title=Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas. | journal=Am J Gastroenterol | year= 2000 | volume= 95 | issue= 9 | pages= 2271-7 | pmid=11007228 | doi=10.1111/j.1572-0241.2000.02480.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11007228  }} </ref>. The advantages are:
 
* It enables visualization of smaller tumors (2 mm)
The advantages are:
* It enables visualization of smaller [[Tumor|tumors]] (2 mm)
* Local metastasis and invasion can be detected
* Local metastasis and invasion can be detected
* Higher spatial resolutions
* Higher resolutions
The disadvantages are : invasiveness, high cost, availabilty and expertise.
The disadvantages are invasiveness, high cost, availability, and expertise.
{{#ev:youtube|TF1phjhRZLg}}
{{#ev:youtube|TF1phjhRZLg}}


===Intra-operative Ultrasound===
===Intra-operative Ultrasound===
The use was introduced in 1981 and used to localise non-palpable lesions and those who are in close proximity to pancreatic and bile ducts. They can localise the tumors in 86% of cases when performed during an open or laproscopic surgery. <ref name="pmid9426437">{{cite journal| author=Brown CK, Bartlett DL, Doppman JL, Gorden P, Libutti SK, Fraker DL et al.| title=Intraarterial calcium stimulation and intraoperative ultrasonography in the localization and resection of insulinomas. | journal=Surgery | year= 1997 | volume= 122 | issue= 6 | pages= 1189-93; discussion 1193-4 | pmid=9426437 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9426437  }} </ref><ref name="pmid16360384">{{cite journal| author=Grover AC, Skarulis M, Alexander HR, Pingpank JF, Javor ED, Chang R et al.| title=A prospective evaluation of laparoscopic exploration with intraoperative ultrasound as a technique for localizing sporadic insulinomas. | journal=Surgery | year= 2005 | volume= 138 | issue= 6 | pages= 1003-8; discussion 1008 | pmid=16360384 | doi=10.1016/j.surg.2005.09.017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16360384  }} </ref>
It was introduced in 1981 and used to localize non-palpable lesions and those who are in close proximity to [[pancreas]] and [[bile ducts]]. This method can localize tumors in 86% of cases when performed during an open or [[Laparoscopic surgery|laparoscopic surgery.]]<ref name="pmid9426437">{{cite journal| author=Brown CK, Bartlett DL, Doppman JL, Gorden P, Libutti SK, Fraker DL et al.| title=Intraarterial calcium stimulation and intraoperative ultrasonography in the localization and resection of insulinomas. | journal=Surgery | year= 1997 | volume= 122 | issue= 6 | pages= 1189-93; discussion 1193-4 | pmid=9426437 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9426437  }} </ref><ref name="pmid16360384">{{cite journal| author=Grover AC, Skarulis M, Alexander HR, Pingpank JF, Javor ED, Chang R et al.| title=A prospective evaluation of laparoscopic exploration with intraoperative ultrasound as a technique for localizing sporadic insulinomas. | journal=Surgery | year= 2005 | volume= 138 | issue= 6 | pages= 1003-8; discussion 1008 | pmid=16360384 | doi=10.1016/j.surg.2005.09.017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16360384  }} </ref>
 
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 19:00, 16 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2] Mohammed Abdelwahed M.D[3]

Overview

Transabdominal ultrasound has low sensitivity varying between 0-66% in detecting insulinoma. The sensitivity increases with the use of more invasive endoscopic ultrasound (93%) and intraoperative ultrasound (86%). Hypoechoic lesion and hypervascular mass are ultrasonographic findings.

Transabdominal Ultrasound

Invasive Ultrasound

Endoscopic Ultrasound

This is an invasive ultrasound which can be done pre-operatively. Its use has been increased with improve in its sensitivity. Endoscopic ultrasound is more accurate for pancreatic head insulinomas. It is the primary diagnostic modality for the diagnosis of pancreatic neuroendocrine tumors (which includes insulinoma).[1][2][3]

The advantages are:

  • It enables visualization of smaller tumors (2 mm)
  • Local metastasis and invasion can be detected
  • Higher resolutions

The disadvantages are invasiveness, high cost, availability, and expertise. {{#ev:youtube|TF1phjhRZLg}}

Intra-operative Ultrasound

It was introduced in 1981 and used to localize non-palpable lesions and those who are in close proximity to pancreas and bile ducts. This method can localize tumors in 86% of cases when performed during an open or laparoscopic surgery.[4][5]

References

  1. 1.0 1.1 McAuley, G.; Delaney, H.; Colville, J.; Lyburn, I.; Worsley, D.; Govender, P.; Torreggiani, W.C. (2005). "Multimodality preoperative imaging of pancreatic insulinomas". Clinical Radiology. 60 (10): 1039–1050. doi:10.1016/j.crad.2005.06.005. ISSN 0009-9260.
  2. Sotoudehmanesh R, Hedayat A, Shirazian N, Shahraeeni S, Ainechi S, Zeinali F; et al. (2007). "Endoscopic ultrasonography (EUS) in the localization of insulinoma". Endocrine. 31 (3): 238–41. PMID 17906369.
  3. Anderson MA, Carpenter S, Thompson NW, Nostrant TT, Elta GH, Scheiman JM (2000). "Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas". Am J Gastroenterol. 95 (9): 2271–7. doi:10.1111/j.1572-0241.2000.02480.x. PMID 11007228.
  4. Brown CK, Bartlett DL, Doppman JL, Gorden P, Libutti SK, Fraker DL; et al. (1997). "Intraarterial calcium stimulation and intraoperative ultrasonography in the localization and resection of insulinomas". Surgery. 122 (6): 1189–93, discussion 1193-4. PMID 9426437.
  5. Grover AC, Skarulis M, Alexander HR, Pingpank JF, Javor ED, Chang R; et al. (2005). "A prospective evaluation of laparoscopic exploration with intraoperative ultrasound as a technique for localizing sporadic insulinomas". Surgery. 138 (6): 1003–8, discussion 1008. doi:10.1016/j.surg.2005.09.017. PMID 16360384.