Hirschsprung's disease other diagnostic studies

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Hirschsprung's disease Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Other diagnostic studies include rectal biopsy, barium enema, and anorectal manometry. A rectal biopsy, which will show an absence of ganglionic cells, is the gold standard confirmatory test for Hirschsprung's disease.[1][2]

Other Diagnostic Studies

A rectal biopsy presenting the absence of ganglionic cells is the gold standard confirmatory test for Hirschsprung's disease.[1][2]

Diagnostic Test Findings
Rectal biopsy
Enema
  • Contracted distal bowel and dilated proximal bowel with demonstration of the transition zone location in between
Anorectal manometry
  • Absent anal reflex and increased pressure

References

  1. 1.0 1.1 Wetherill C, Sutcliffe J (2014). "Hirschsprung disease and anorectal malformation". Early Hum. Dev. 90 (12): 927–32. doi:10.1016/j.earlhumdev.2014.09.016. PMID 25448783.
  2. 2.0 2.1 Das K, Mohanty S (2017). "Hirschsprung Disease - Current Diagnosis and Management". Indian J Pediatr. doi:10.1007/s12098-017-2371-8. PMID 28600660.

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