High density lipoprotein complete list of trials
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
Reconstituted HDL Infusion
| Name of the Trial | Official Name | Status | |
| CHI-SQUARE Study | CHI SQUARE: Can HDL Infusions Significantly Quicken Atherosclerosis Regression? A Phase II, Multi-Center, Double-Blind, Ascending Dose, Placebo-Controlled, Dose-Finding Trial of CER-001 or Placebo in Subjects With Acute Coronary Syndrome | Ongoing | |
| CSL-112 Trial - Phase 1 | An Adaptive, Phase I, Randomised, Placebo-controlled, Sponsor-unblinded, Multiple Ascending Dose Study to Investigate the Safety, Tolerability and Pharmacokinetics of Intravenous CSL112 in Healthy Volunteers | Completed | |
| CSL-112 Trial - Phase 1 | An Adaptive, Phase I, Single-Centre, Randomised, Double-blind, Placebo-controlled Single Ascending Dose Study to Investigate the Safety, Tolerability and Pharmacokinetics, of Intravenous CSL112 in Healthy Volunteers | Completed | |
| CSL-112 Trial - Phase 2 | A Phase 2a, Multi-center, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study to Investigate the Safety, Tolerability and Pharmacokinetics of a Single Intravenous Infusion of CSL112in Patients With Stable Atherothrombotic Disease | Completed | |
| ERASE Trial | Regression of Coronary Atherosclerotic Lesions After rHDL Infusions in Acute Coronary Syndrome Patients as Assessed by Intravascular Ultrasound | Completed | |
| Infusion of Apo A-1 Milano | A Phase III Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor AEGR-733 in Patients With Homozygous Familial Hypercholesterolemia on Current Lipid-lowering Therapy | Completed |
CETP Inhibitors
| ACCELERATE Trial | Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition With Evacetrapib in Patients at a High-Risk for Vascular Outcomes | Ongoing | |
| dal-OUTCOMES Trial | A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome | Completed | |
| DEFINE Trial | |||
| ILLUMINATE Trial | |||
| ILLUSTRATE Trial | |||
| REVEAL Trial |
Niacin
| AIM-HIGH Trial |
| ARBITER 2 Trial |
| ARBITER 3 Trial |
| ARBITER 6-HALTS Trial |
| CLAS Trial |
| HATS Trial |
| Oxford Niaspan Study |
Fibrate
| VA-HIT Trial |
| BECAIT Trial |
| BIP Trial |
Statin
| ASTEROID Trial |
| SATURN Trial |
| 4S Trial |
| CORONA Trial |
Multiple Lipid Lowering Drugs
| HARP Study |
| AFREGS Trial |
Other trials
| Name of the Trial | Official Name | Status | |
| A Study of LY2484595 in Patients With High LDL-C or Low HDL-C | A Phase 2 Efficacy and Safety Study of LY2484595 Alone and in Combination With Atorvastatin, Simvastatin, and Rosuvastatin in Patients With Hypercholesterolemia or Low HDL-C | Completed | |
| A Study of LY2484595 in Japanese Subjects | A Phase 2 Dose Response Study of LY2484595 in Japanese Subjects | Completed | |
| A Study of LY2484595 on Pharmacokinetics in Healthy Subjects | A Phase 1 Study to Evaluate the Safety and Tolerability of LY2484595 SDSD-PG Tablets and the Effect of CYP3A Inhibition by Ketoconazole on the Pharmacokinetics of LY2484595 in Healthy Subjects | Completed |
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