Hepatitis D risk factors: Difference between revisions

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==Overview==
==Overview==
Risk factors for hepatitis D, either coinfection or superinfection with [[HBV]], include: IV drug use; infection during pregnancy; sexual intercourse with infected persons; exposure to unscreened blood or blood products; hemodyalisis patients; and healthcare and public service workers dealing with infected patients.
Common risk factors in the development of hepatitis D include  [[intravenous drug use]], sexual intercourse with infected individuals, [[hemodialysis]], and occupational exposure to infected individuals and blood products <ref name=WHO>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref><ref name=CDC>{{cite web | title = Hepatitis D (CDC) | url = http://www.cdc.gov/hepatitis/HDV/index.htm }}</ref>.


== Risk Factors ==
== Risk Factors ==
Since [[HDV]] requires the support of [[hepatitis B virus]] for its own replication, inoculation with [[HDV]] in the absence of [[HBV]] will not cause [[hepatitis D]]. Alone, the [[viral]] [[genome]] indeed replicates in a helper-independent manner, but virus particles are not released.<ref name=WHO>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref><ref name=CDC>{{cite web | title = Hepatitis D (CDC) | url = http://www.cdc.gov/hepatitis/HDV/index.htm }}</ref>
Since [[HDV]] requires the support of [[hepatitis B virus]] for its own replication, inoculation with [[HDV]] in the absence of [[HBV]] will not cause [[hepatitis D]]. Alone, the [[viral]] [[genome]] replicates in a helper-independent manner, but the viral particles do not exit the cell.<ref name=WHO>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref><ref name=CDC>{{cite web | title = Hepatitis D (CDC) | url = http://www.cdc.gov/hepatitis/HDV/index.htm }}</ref>


When in the presence of [[hepatitis B virus]], [[risk factor]]s for [[hepatitis D]] include:
When in the presence of [[hepatitis B virus]], [[risk factor]]s for [[hepatitis D]] include:
* Using [[intravenous]] (IV) or injection drugs
* Using [[intravenous]] ([[IV]]) or injection drugs
* Being infected while pregnant (the mother can pass the virus to the baby)
* Being infected while pregnant (the mother can pass the virus to the baby)
* Carrying the [[hepatitis B virus]]
* Carrying the [[hepatitis B virus]]
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* People exposed to unscreened [[blood]] or [[blood]] products
* People exposed to unscreened [[blood]] or [[blood]] products
* [[Haemophilia|Haemophiliacs]]
* [[Haemophilia|Haemophiliacs]]
*[[Hemodialysis]] patients  
* [[Hemodialysis]] patients  
* Health care and public safety workers  
* Health care and public safety workers  
* Individuals who are not infected with [[HBV]], and have not been [[vaccine|immunized]] against [[HBV]], are at risk of [[infection]] with [[HBV]] with simultaneous or subsequent infection with [[HDV]].
* Individuals who are not infected with [[HBV]], and have not been [[vaccine|immunized]] against [[HBV]], are at risk of [[infection]] with [[HBV]] with simultaneous or subsequent infection with [[HDV]].
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==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}
[[Category:Hepatitis|D]]
[[Category:Hepatitis|D]]
[[Category:Viruses]]
[[Category:Viruses]]
 
[[Category:Emergency mdicine]]
{{WH}}
[[Category:Disease]]
{{WS}}
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Hepatology]]
[[Category:Gastroenterology]]

Latest revision as of 22:06, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2] Jolanta Marszalek, M.D. [3]

Overview

Common risk factors in the development of hepatitis D include intravenous drug use, sexual intercourse with infected individuals, hemodialysis, and occupational exposure to infected individuals and blood products [1][2].

Risk Factors

Since HDV requires the support of hepatitis B virus for its own replication, inoculation with HDV in the absence of HBV will not cause hepatitis D. Alone, the viral genome replicates in a helper-independent manner, but the viral particles do not exit the cell.[1][2]

When in the presence of hepatitis B virus, risk factors for hepatitis D include:

  • Using intravenous (IV) or injection drugs
  • Being infected while pregnant (the mother can pass the virus to the baby)
  • Carrying the hepatitis B virus
  • Men having sexual intercourse with other men
  • Sexual intercourse with HDV infected persons
  • Receiving many blood transfusions
  • People exposed to unscreened blood or blood products
  • Haemophiliacs
  • Hemodialysis patients
  • Health care and public safety workers
  • Individuals who are not infected with HBV, and have not been immunized against HBV, are at risk of infection with HBV with simultaneous or subsequent infection with HDV.

References

  1. 1.0 1.1 "Hepatitis D" (PDF).
  2. 2.0 2.1 "Hepatitis D (CDC)".

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