Gallbladder cancer overview: Difference between revisions

Jump to navigation Jump to search
(Mahshid)
No edit summary
Line 7: Line 7:
__NOTOC__
__NOTOC__
{{Gallbladder cancer}}
{{Gallbladder cancer}}
{{CMG}}{{AE}}{{PSD}}
{{CMG}}{{AE}}{{VKG}}


==Overview==
==Overview==

Revision as of 19:49, 30 January 2018

https://https://www.youtube.com/watch?v=WsmW6I0cmBE%7C350}}

Gallbladder cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Differentiating Gallbladder cancer from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

CT

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Palliative Treatment

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Gallbladder cancer overview On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Gallbladder cancer overview

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Gallbladder cancer overview

CDC on Gallbladder cancer overview

Gallbladder cancer overview in the news

Blogs on Gallbladder cancer overview

Directions to Hospitals Treating Gallbladder cancer

Risk calculators and risk factors for Gallbladder cancer overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

Classification

Gallbladder cancer may be classified according to histology findings into various subtypes.

Pathophysiology

The pathophysiology of gallbladder cancer depends on the histologic subtypes.

Epidemiology and Demographics

In 2015, the number of new cases of gallbladder cancer was estimated to be 10,910 in United States. Females are more commonly affected with gallbladder cancer than males, the female to male ratio is approximately 5 to 1.

Risk factors

Common risk factors in the development of gallbladder cancer are obesity, chronic cholecystitis, chronic cholelithiasis, chronic typhoid infection, alcohol and genetic mutations.

Screening

There is no screening recommended for gallbladder cancer.

Differential Diagnosis

Gallbladder cancer must be differentiated from hepatitis, gallstones, cholecystitis, peptic ulcer, pancreatic cancer and pancreatitis.

Natural history, Complications and prognosis

Depending on the extent of the tumor at the time of diagnosis, the prognosis is generally regarded as poor.

Staging

According to the AJCC, there are 4 stages of gallbladder cancer based on the tumor spread.

History and symptoms

Symptoms of gallbladder cancer include jaundice, pain, fever, burping and weight loss.

Laboratory findings

Laboratory findings consistent with the diagnosis of gallbladder cancer include abnormal liver function tests and elevated CA 19-9 and CEA levels.

CT

On abdominal CT scan, gallbladder cancer appears as large heterogeneous mass with areas of necrosis.

MRI

MRI combined with magnetic resonance cholangiography may be helpful in the diagnosis of gallbladder cancer metastasis.

Other imaging findings

PET scan may be helpful in the diagnosis of gallbladder cancer.

Medical therapy

The therapy for gallbladder cancer depends largely on the disease progression and the stage of cancer.

Surgery

The mainstay of therapy for gallbladder cancer is surgery.

Palliative treatment

Palliative therapy in gallbladder cancer involves percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, standard external-beam radiation therapy, palliative surgery or standard chemotherapy.

Primary Prevention

Research suggests that lifestyle factors such as changes in diet, exercise, and maintenance of weight can influence the likelihood of an individual developing gallbladder cancer.

References


Template:WikiDoc Sources