Friedreich's ataxia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D

Overview

Because Friedreich’s Ataxia is a genetic diseases transmitted by autosomal recessive pattern, the most potent risk factor in the development of Friedreich’s Ataxia is strong family history. Other risk factors are unknown. The risk factors for developing associated clinical conditions of Friedreich's ataxia include: GAA1 length and age of diagnosis.

Risk Factors

  • Because Friedreich’s Ataxia is a genetic diseases transmitted by autosomal recessive pattern, the most potent risk factor in the development of Friedreich’s Ataxia is strong family history. Other risk factors are unknown.
  • The risk factors for developing associated clinical conditions of Friedreich's ataxia include:[1]
    • GAA1 length
    • Age of diagnosis

References

  1. Lazo JS, Hait WN, Kennedy KA, Braun ID, Meandzija B (March 1985). "Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists". Mol. Pharmacol. 27 (3): 387–93. PMID 2579318.