Fibroma causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2], Simrat Sarai, M.D. [3]

Overview

Common causes of oral fibroma include trauma or chronic irritation. There are no established causes for chondromyxoid fibroma, non-ossifying fibroma, cemento-ossifying fibroma, and ossifying fibroma. Although there are some associated factors for the development of some fibromas like ovarian fibroma, uterine fibroma.


Type of fibroma	Causes/ associated factors
Ovarian Fibroma	Obesity Tamoxifen therapy Early menarche Infertility Nulliparity African race Estrogen
Non-ossifying Fibroma	Clonal rearrangements in chromosomes 1, 3, 4, 11, and 14
Uterine Fibroma ^[1]	Genetic changes Estrogen and progesterone Insulin-like growth factor
Oral Fibroma	Trauma or chronic irritation
Chondromyxoid Fibroma	Clonal rearrangement of chromosome 6

↑ Okolo S (August 2008). "Incidence, aetiology and epidemiology of uterine fibroids". Best Pract Res Clin Obstet Gynaecol. 22 (4): 571–88. doi:10.1016/j.bpobgyn.2008.04.002. PMID 18534913.