Extranodal NK-T-cell lymphoma staging: Difference between revisions
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* Another parallel mechanism for extranodal NK/T cell lymphoma is based on [[tumor]] [[Biology|biologic]] and micro-environmental factors. High Ki-67 [[nuclear]] antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk. | * Another parallel mechanism for extranodal NK/T cell lymphoma is based on [[tumor]] [[Biology|biologic]] and micro-environmental factors. High Ki-67 [[nuclear]] antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.<ref name="pmid24642368">{{cite journal |vauthors=Huang X, Sun Q, Fu H, Zhou X, Guan X, Wang J |title=Both c-Myc and Ki-67 expression are predictive markers in patients with extranodal NK/T-cell lymphoma, nasal type: a retrospective study in China |journal=Pathol. Res. Pract. |volume=210 |issue=6 |pages=351–6 |date=June 2014 |pmid=24642368 |doi=10.1016/j.prp.2014.02.004 |url=}}</ref> | ||
==References== | ==References== |
Revision as of 15:23, 25 September 2019
Extranodal NK-T-cell lymphoma Microchapters |
Differentiating Extranodal NK-T-cell lymphoma from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Extranodal NK-T-cell lymphoma staging On the Web |
American Roentgen Ray Society Images of Extranodal NK-T-cell lymphoma staging |
Risk calculators and risk factors for Extranodal NK-T-cell lymphoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system. A new system was introduced based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined. Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.
Staging
- Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system.
- A new system was introduced by a Korean study based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined.Four risk groups identified as below:
- group 1: No adverse factor
- group 2: One factor
- group 3: Two factors
- group 4: Three or more factors
Group | Altered factors count | 5 year prognosis |
---|---|---|
1 | N.O. | 81000 out of 100000 |
2 | 1 | 64000 out of 100000 |
3 | 2 | 34000 out of 100000 |
4 | 3/More | 7000 out of 100000 |
- Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.[1]
References
- ↑ Huang X, Sun Q, Fu H, Zhou X, Guan X, Wang J (June 2014). "Both c-Myc and Ki-67 expression are predictive markers in patients with extranodal NK/T-cell lymphoma, nasal type: a retrospective study in China". Pathol. Res. Pract. 210 (6): 351–6. doi:10.1016/j.prp.2014.02.004. PMID 24642368.