Extranodal NK-T-cell lymphoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: , Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
The most common symptoms of extranodal NK-T-cell lymphoma include fever, weight loss, skin rash, night sweats, protrusion of eye, swelling of the face, discharge from the nose, nose bleeds, blockage of the nasal passages, chest pain, abdominal pain, bone pain, and painless swelling in the neck, axilla, groin, thorax, and abdomen. Extranodal NK/T cell lymphoma, nasal type, which is the most common sub type, is usually found as an ulcerative and necrotic granuloma in the nasal cavity, palate, and nasopharynx. Tumor can spread to surrounding tissue such as facial skin, paranasal sinus, and orbits, and cause exensive destruction of midline lesions. The most common symptoms at the time of diagnosis are nasal obstruction and bloody rhinorea.
Symptoms
- Symptoms of the extranodal NK-T-cell lymphoma include:[1][2][3][4]
- Fever
- Weight loss
- Night sweats
- Protrusion of eye
- Swelling of the face
- Discharge from the nose
- Nose bleeds
- Blockage of the nasal passages
- Skin rash
- Chest pain
- Abdominal pain
- Bone pain
- Painless swelling in the neck, axilla, groin, thorax, and abdomen
- Bloody rhinorrhea
- B symptoms
- Extranodal NK/T cell lymphoma, nasal type, which is the most common subtype, is usually found as an ulcerative and necrotic granuloma in the nasal cavity, palate, and nasopharynx.[5] [6]
- Tumor can spread to surrounding tissue such as facial skin, paranasal sinus, and orbits, and cause extensive destruction of midline lesions.
- The most common symptoms at the time of diagnosis are nasal obstruction and bloody rhinorrhea.[7]
References
- ↑ Extranodal NK-/T-cell lymphoma, nasal type. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd530f/. Accessed on February 02, 2016
- ↑ Extranodal NK/T-cell lymphoma, nasal type. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/extranodal-nk-t-cell-lymphoma-nasal-type/?region=on. Accessed on February 04, 2016
- ↑ Extranodal Natural-Killer/T-Cell Lymphoma, Nasal Type. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2010/627401/. Accessed on February 19, 2016
- ↑ Wu, X.; Li, P.; Zhao, J.; Yang, X.; Wang, F.; Yang, Y.Q.; Fang, F.; Xu, Y.; Zhang, H.; Wang, W.Y.; Yi, C. (2008). "A Clinical Study of 115 Patients with Extranodal Natural Killer/T-cell Lymphoma, Nasal Type". Clinical Oncology. 20 (8): 619–625. doi:10.1016/j.clon.2008.05.011. ISSN 0936-6555.
- ↑ Harabuchi, Yasuaki; Kataura, Akikatsu; Kobayashi, Kazutoyo; Yamamoto, Tetsuo; Yamanaka, Noboru; Hirao, Motoyasu; Onodera, Kazufumi; Kon, Shinichiro (1992). "Lethal midline granuloma (peripheral T-cell lymphoma) after lymphomatoid papulosis". Cancer. 70 (4): 835–839. doi:10.1002/1097-0142(19920815)70:4<835::AID-CNCR2820700419>3.0.CO;2-F. ISSN 0008-543X.
- ↑ Harabuchi, Y.; Yamanaka, N.; Kataura, A.; Imai, S.; Kinoshita, T.; Osato, T. (1990). "Epstein-Barr virus in nasal T-cell lymphomas in patients with lethal midline granuloma". The Lancet. 335 (8682): 128–130. doi:10.1016/0140-6736(90)90002-M. ISSN 0140-6736.
- ↑ Wu, X.; Li, P.; Zhao, J.; Yang, X.; Wang, F.; Yang, Y.Q.; Fang, F.; Xu, Y.; Zhang, H.; Wang, W.Y.; Yi, C. (2008). "A Clinical Study of 115 Patients with Extranodal Natural Killer/T-cell Lymphoma, Nasal Type". Clinical Oncology. 20 (8): 619–625. doi:10.1016/j.clon.2008.05.011. ISSN 0936-6555.