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==[[Erythroleukemia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Erythroleukemia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


==Diagnosis==
[[Erythroleukemia history and symptoms|History and Symptoms]] | [[Erythroleukemia physical examination|Physical Examination]] | [[Erythroleukemia laboratory findings|Laboratory Findings]] | [[Erythroleukemia chest x ray|Chest X Ray]] | [[Erythroleukemia CT|CT]] | [[Erythroleukemia MRI|MRI]] | [[Erythroleukemia echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Erythroleukemia other diagnostic studies|Other Diagnostic Studies]]


'''Erythroleukemia''' (or "acute Di Guglielmo syndrome") is a rare form of [[acute myeloid leukemia]] where the [[myeloproliferation]] is of [[erythrocyte]] precursors.
==Treatment==


It is defined at type "M6" under the [[Acute myelogenous leukemia#French-American-British .28FAB.29 classification|FAB classification]].<ref name="urlAcute Myeloid Leukemia - Signs and Symptoms">{{cite web |url=http://www.ucsfhealth.org/adult/medical_services/cancer/leukemia/conditions/aml/signs.html |title=Acute Myeloid Leukemia - Signs and Symptoms |format= |work=}}</ref>
[[Erythroleukemia medical therapy|Medical Therapy]] | [[Erythroleukemia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Erythroleukemia future or investigational therapies|Future or Investigational Therapies]]


===Types===
==Case Studies==
It can be classified as follows:
* M6a; Erythroid/Myeloid


* M6b; Pure Erythroid Malignancy
:[[Erythroleukemia case study one|Case #1]]


==Criteria for diagnosis of M6==


===M6a===
50% or more of all nucleated bone marrow cells are erythroblasts, Dyserythropoiesis is prominent and 30% or more of the remaining cells (non- erythroid) are myeloblasts.
===M6b ( Pure Erythroid Malignancy )===
In rare cases the erythroid lineage is the only obvious components of an acute leukemia; a myeloblast component is not apparent. The erythroid component consists predominantly or exclusively of proerythroblasts and early basophilic erythroblasts. These cells may constitute 90% or more of the marrow elements. Despite this lack of myeloblast, these cases should be considered acute leukemias. In WHO proposal the blastic leukeimas that are limited to the erythroid series are designated pure erythroid malignancy.


==Related chapters==
==Related chapters==
*[[Acute myeloid leukemia]]
*[[Acute myeloid leukemia]]


==Resources==
* [http://www.meds.com/leukemia/atlas/leuk7.html Atlas of Acute Leukemia]
==References==
{{cite journal |author=Kowal-Vern A, Mazzella FM, Cotelingam JD, Shrit MA, Rector JT, Schumacher HR |title=Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases |journal=Am. J. Hematol. |volume=65 |issue=1 |pages=5-13 |year=2000 |pmid=10936857 |doi=}}
{{reflist|2}}


[[Category:Disease]]
[[Category:Disease]]

Revision as of 20:43, 12 September 2012

Template:DiseaseDisorder infobox Template:Erythroleukemia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Acute erythroid leukemia; acute Di Guglielmo syndrome; erythroleukemia

Overview

Classification

Pathophysiology

Causes

Differentiating Erythroleukemia from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Diagnostic Studies

Treatment

Medical Therapy | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1


Related chapters


Template:WikiDoc Sources

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