Epidermodysplasia verruciformis
| Epidermodysplasia verruciformis | |
| OMIM | 226400 305350 |
|---|---|
| DiseasesDB | 31394 |
| eMedicine | derm/123 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Epidermodysplasia verruciformis (also called Lewandowsky-Lulz dysplasia or Lulz-Lewandowsky epidermodysplasia verruciformis) is an extremely rare skin disease characterized by the growth of scaly macules and papules, particularly on the hands. Named after doctors Felix Lewandowsky and Wilhelm Lulz,[1] the condition usually begins in childhood and has no known cure.
It is believed to be caused by the human papillomavirus and is most strongly associated with strains 5 and 8, although others may also contribute. Genetic predisposition is also thought to partly explain why the disease is so rare, as EV papillomaviruses are often found (15-20%) in normal skin with no increased incidence of cancer.
Notable cases
In March 2007, a Romanian man was diagnosed with this condition. The man, patient of dermatologist Dr. Carmen Madeleine Curea, quickly became an internet meme, his pictures appearing on numerous blogs[2] and Romanian press sources.[3] Dr. Curea works out of Spitalului Clinic Colentina in Bucharest, Romania.[4] Stephen Stone, past president of the American Academy of Dermatology, confirms this is Lewandowsky-Lutz.[5]
Further reading
- H. Sadakane, Y. Yabe. The Virus of Epidermodysplasia Verruciformis: Electron Microscopic and Fluorescent Antibody Studies. Journal of Investigative Dermatology (1975) 65, 324–330 [2]
- F. Lewandowsky, W. Lulz. Ein Fall einer bisher noch nicht beschriebener Hauterkrankung (Epidermodysplasia verruciformis). Archiv für Dermatologie und Syphilis (1922) 141, 193-202.
References
- ↑ Lewandowsky-Lulz dysplasia: Who Named It?
- ↑ http://www.markallencam.com/?p=155
- ↑ http://petricapatilea.directnews.ro/2007/03/13/cernobal-inca-loveste/ Cernobal inca loveste!
- ↑ http://www.sisnet.ro/index.php?page=articol&id=14684
- ↑ http://www.revolutionhealth.com/blogs/valjonesmd/rare-skin-disorder-ma-2928 Rare skin disorder may be triggered by wart virus?