Epidermodysplasia verruciformis
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| Epidermodysplasia verruciformis Classification and external resources | |
| OMIM | 226400 305350 |
|---|---|
| DiseasesDB | 31394 |
| eMedicine | derm/123 |
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Epidermodysplasia verruciformis (also called Lewandowsky-Lulz dysplasia or Lulz-Lewandowsky epidermodysplasia verruciformis) is an extremely rare skin disease characterized by the growth of scaly macules and papules, particularly on the hands. Named after doctors Felix Lewandowsky and Wilhelm Lulz,[1] the condition usually begins in childhood and has no known cure.
It is believed to be caused by the human papillomavirus and is most strongly associated with strains 5 and 8, although others may also contribute. Genetic predisposition is also thought to partly explain why the disease is so rare, as EV papillomaviruses are often found (15-20%) in normal skin with no increased incidence of cancer.
Notable cases
In March 2007, a Romanian man was diagnosed with this condition. The man, patient of dermatologist Dr. Carmen Madeleine Curea, quickly became an internet meme, his pictures appearing on numerous blogs[1] and Romanian press sources.[1] Dr. Curea works out of Spitalului Clinic Colentina in Bucharest, Romania.[1] Stephen Stone, past president of the American Academy of Dermatology, confirms this is Lewandowsky-Lutz.[1]
Further reading
- H. Sadakane, Y. Yabe. The Virus of Epidermodysplasia Verruciformis: Electron Microscopic and Fluorescent Antibody Studies. Journal of Investigative Dermatology (1975) 65, 324–330 [3]
- F. Lewandowsky, W. Lulz. Ein Fall einer bisher noch nicht beschriebener Hauterkrankung (Epidermodysplasia verruciformis). Archiv für Dermatologie und Syphilis (1922) 141, 193-202.
References
External links
- Who Named It?
- The Doctor's Doctor
- Atlas of Genetics and Cytogenetics in Oncology and Haematology
- IDR factfile
- DermIS
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
