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==Overview==
==Overview==
==Historical Perspective==
*This transformation of the liver was identified by the first anatomic pathologist, Gianbattista Morgagni in his 500 autopsies published in 1761. but the name of "cirrhosis" (greek=orange color) was given by Laennec in 1826 because of the yellowish-tan color of the cirrhotic liver. Only in 1930, one hundred years later, however, the first theory as to the pathogenesis of this disorder was advanced by Roessle: parenchymal degeneration, regeneration and scarring which is now understood according to the following sequence:


The word "cirrhosis" is a neologism that derives from Greek ''kirrhos'', meaning "tawny" (the orange-yellow colour of the diseased liver). While the clinical entity was known before, it was [[René Laennec]] who gave it the name "cirrhosis" in his 1819 work in which he also describes the stethoscope.<ref>Roguin A. Rene Theophile Hyacinthe Laennec (1781-1826): the man behind the stethoscope. ''Clin Med Res'' 2006;4:230-5. PMID 17048358.</ref>
The word "cirrhosis" is a neologism that derives from Greek ''kirrhos'', meaning "tawny" (the orange-yellow colour of the diseased liver). While the clinical entity was known before, it was [[René Laennec]] who gave it the name "cirrhosis" in his 1819 work in which he also describes the stethoscope.<ref>Roguin A. Rene Theophile Hyacinthe Laennec (1781-1826): the man behind the stethoscope. ''Clin Med Res'' 2006;4:230-5. PMID 17048358.</ref>

Revision as of 19:13, 6 September 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Historical Perspective

  • This transformation of the liver was identified by the first anatomic pathologist, Gianbattista Morgagni in his 500 autopsies published in 1761. but the name of "cirrhosis" (greek=orange color) was given by Laennec in 1826 because of the yellowish-tan color of the cirrhotic liver. Only in 1930, one hundred years later, however, the first theory as to the pathogenesis of this disorder was advanced by Roessle: parenchymal degeneration, regeneration and scarring which is now understood according to the following sequence:

The word "cirrhosis" is a neologism that derives from Greek kirrhos, meaning "tawny" (the orange-yellow colour of the diseased liver). While the clinical entity was known before, it was René Laennec who gave it the name "cirrhosis" in his 1819 work in which he also describes the stethoscope.[1]


References

  1. Roguin A. Rene Theophile Hyacinthe Laennec (1781-1826): the man behind the stethoscope. Clin Med Res 2006;4:230-5. PMID 17048358.



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