Chronic stable angina cardiac magnetic resonance imaging: Difference between revisions
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{{Chronic stable angina}} | {{Chronic stable angina}} | ||
''' | '''Editor-In-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; '''Associate Editor(s)-in-Chief:''' {{CZ}}; Smita Kohli, M.D.; [[Lakshmi Gopalakrishnan]], M.B.B.S. | ||
==Cardiac | ==Overview== | ||
Cardiac magnetic resonance imaging (CMRI) is a non-invasive test that is useful in the evaluation of overall coronary anatomy and function, and also holds a potential for '''plaque characterization''' . | |||
==Indications for CMR based on Consensus Panel report <ref name="pmid15522474">Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE et al. (2004) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=15522474 Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report.] ''Eur Heart J'' 25 (21):1940-65. [http://dx.doi.org/10.1016/j.ehj.2004.06.040 DOI:10.1016/j.ehj.2004.06.040] PMID: [http://pubmed.gov/15522474 15522474]</ref>== | |||
{{cquote| | |||
===Class I=== | |||
'''1.''' Assessment of global ventricular (left and right) function and mass | |||
'''2.''' Detection of [[coronary artery disease]] | |||
:'''a.''' Coronary MRA (anomalies) | |||
'''3.''' Acute and chronic [[myocardial infarction]] | |||
:'''a.''' Detection and assessment | |||
:'''b.''' Myocardial viability | |||
*Stress wall motion abnormalities | ===Class II=== | ||
*Myocardial perfusion | '''1.''' Detection of coronary artery disease | ||
*Coronary angiography and coronary flow evaluation | :'''a.''' [[Chronic stable angina risk stratification based upon rest left ventricular function|Regional left ventricular function at rest]] and during [[Chronic stable angina perfusion scintigraphy with pharmacologic stress|dobutamine stress]] | ||
:'''b.''' Assessment of myocardial perfusion | |||
:'''c.''' Coronary MRA of bypass graft patency | |||
'''2.''' Acute and chronic myocardial infarction | |||
:'''a.''' Ventricular thrombus | |||
===Class III=== | |||
'''1.''' Detection of coronary artery disease | |||
:'''a.''' Coronary MRA (CAD) | |||
'''2.''' Acute and chronic myocardial infarction | |||
:'''a.''' [[Ventricular septal defect]] | |||
:'''b.''' [[Mitral regurgitation]] (acute MI) | |||
===Class Inv=== | |||
'''1.''' Detection of coronary artery disease | |||
:'''a.''' MR flow measurements in the coronary arteries | |||
:'''b.''' Arterial wall imaging | |||
'''2.''' Acute and chronic myocardial infarction | |||
:'''a.''' [[Acute coronary syndromes]]}} | |||
''Note:'' | |||
*Class I: provides clinically relevant information and is usually appropriate; may be used as first line imaging technique; usually supported by substantial literature. | |||
*Class II: provides clinically relevant information and is frequently useful; other techniques may provide similar information; supported by limited literature. | |||
*Class III: provides clinically relevant information but is infrequently used because information from other imaging techniques is usually adequate. | |||
*Class Inv: potentially useful, but still investigational. | |||
==Detection of CAD== | |||
*'''Early detection''' of [[atherosclerosis]] and endothelial dysfunction using CMRI is possible with arterial wall imaging and assessing the reactivity of brachial artery. | |||
*Alternative approaches include: | |||
:*Visualization of the effects of induced [[ischemia]] (wall motion, perfusion) | |||
::*'''Stress wall motion abnormalities:''' In patients with [[CAD]], dobutamine stress CMR is helpful to identify ischemia-induced wall motion abnormalities <ref name="pmid11816623">Nagel E, Lorenz C, Baer F, Hundley WG, Wilke N, Neubauer S et al. (2001) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11816623 Stress cardiovascular magnetic resonance: consensus panel report.] ''J Cardiovasc Magn Reson'' 3 (3):267-81. PMID: [http://pubmed.gov/11816623 11816623]</ref> and is considered effective is patients who are unsuitable for dobutamine echocardiography <ref name="pmid10525488">Hundley WG, Hamilton CA, Thomas MS, Herrington DM, Salido TB, Kitzman DW et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10525488 Utility of fast cine magnetic resonance imaging and display for the detection of myocardial ischemia in patients not well suited for second harmonic stress echocardiography.] ''Circulation'' 100 (16):1697-702. PMID: [http://pubmed.gov/10525488 10525488]</ref>. | |||
::*'''Myocardial perfusion:''' In patients with [[CAD]], CMR showed improvement in myocardial perfusion after coronary angioplasty <ref name="pmid11079658">Al-Saadi N, Nagel E, Gross M, Schnackenburg B, Paetsch I, Klein C et al. (2000) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11079658 Improvement of myocardial perfusion reserve early after coronary intervention: assessment with cardiac magnetic resonance imaging.] ''J Am Coll Cardiol'' 36 (5):1557-64. PMID: [http://pubmed.gov/11079658 11079658]</ref> and in patients with [[Syndrome X|cadiac syndrome X]] impaired sub-endocardial perfusion was observed <ref name="pmid12075055">Panting JR, Gatehouse PD, Yang GZ, Grothues F, Firmin DN, Collins P et al. (2002) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12075055 Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging.] ''N Engl J Med'' 346 (25):1948-53. [http://dx.doi.org/10.1056/NEJMoa012369 DOI:10.1056/NEJMoa012369] PMID: [http://pubmed.gov/12075055 12075055]</ref>. | |||
:*Direct visualization of coronary arteries (coronary angiography and flow) | |||
::*'''Coronary angiography and coronary flow evaluation:''' Coronary flow reserve is useful in the identification of LAD stenosis <ref name="pmid10385498">Hundley WG, Hamilton CA, Clarke GD, Hillis LD, Herrington DM, Lange RA et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10385498 Visualization and functional assessment of proximal and middle left anterior descending coronary stenoses in humans with magnetic resonance imaging.] ''Circulation'' 99 (25):3248-54. PMID: [http://pubmed.gov/10385498 10385498]</ref> and in-stent restenosis <ref name="pmid12665488">Nagel E, Thouet T, Klein C, Schalla S, Bornstedt A, Schnackenburg B et al. (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12665488 Noninvasive determination of coronary blood flow velocity with cardiovascular magnetic resonance in patients after stent deployment.] ''Circulation'' 107 (13):1738-43. [http://dx.doi.org/10.1161/01.CIR.0000060542.79482.81 DOI:10.1161/01.CIR.0000060542.79482.81] PMID: [http://pubmed.gov/12665488 12665488]</ref>. CMR imaging is also very accurate in the prediction of graft patency <ref name="pmid11756716">Langerak SE, Kunz P, Vliegen HW, Jukema JW, Zwinderman AH, Steendijk P et al. (2002) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11756716 MR flow mapping in coronary artery bypass grafts: a validation study with Doppler flow measurements.] ''Radiology'' 222 (1):127-35. PMID: [http://pubmed.gov/11756716 11756716]</ref>. | |||
==References== | ==References== |
Revision as of 02:01, 16 August 2011
Chronic stable angina Microchapters | ||
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Differentiating Chronic Stable Angina from Acute Coronary Syndromes | ||
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Alternative Therapies for Refractory Angina | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Smita Kohli, M.D.; Lakshmi Gopalakrishnan, M.B.B.S.
Overview
Cardiac magnetic resonance imaging (CMRI) is a non-invasive test that is useful in the evaluation of overall coronary anatomy and function, and also holds a potential for plaque characterization .
Indications for CMR based on Consensus Panel report [1]
“ |
Class I1. Assessment of global ventricular (left and right) function and mass 2. Detection of coronary artery disease
3. Acute and chronic myocardial infarction
Class II1. Detection of coronary artery disease
2. Acute and chronic myocardial infarction
Class III1. Detection of coronary artery disease
2. Acute and chronic myocardial infarction
Class Inv1. Detection of coronary artery disease
2. Acute and chronic myocardial infarction |
” |
Note:
- Class I: provides clinically relevant information and is usually appropriate; may be used as first line imaging technique; usually supported by substantial literature.
- Class II: provides clinically relevant information and is frequently useful; other techniques may provide similar information; supported by limited literature.
- Class III: provides clinically relevant information but is infrequently used because information from other imaging techniques is usually adequate.
- Class Inv: potentially useful, but still investigational.
Detection of CAD
- Early detection of atherosclerosis and endothelial dysfunction using CMRI is possible with arterial wall imaging and assessing the reactivity of brachial artery.
- Alternative approaches include:
- Visualization of the effects of induced ischemia (wall motion, perfusion)
- Myocardial perfusion: In patients with CAD, CMR showed improvement in myocardial perfusion after coronary angioplasty [4] and in patients with cadiac syndrome X impaired sub-endocardial perfusion was observed [5].
- Direct visualization of coronary arteries (coronary angiography and flow)
References
- ↑ Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE et al. (2004) Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J 25 (21):1940-65. DOI:10.1016/j.ehj.2004.06.040 PMID: 15522474
- ↑ Nagel E, Lorenz C, Baer F, Hundley WG, Wilke N, Neubauer S et al. (2001) Stress cardiovascular magnetic resonance: consensus panel report. J Cardiovasc Magn Reson 3 (3):267-81. PMID: 11816623
- ↑ Hundley WG, Hamilton CA, Thomas MS, Herrington DM, Salido TB, Kitzman DW et al. (1999) Utility of fast cine magnetic resonance imaging and display for the detection of myocardial ischemia in patients not well suited for second harmonic stress echocardiography. Circulation 100 (16):1697-702. PMID: 10525488
- ↑ Al-Saadi N, Nagel E, Gross M, Schnackenburg B, Paetsch I, Klein C et al. (2000) Improvement of myocardial perfusion reserve early after coronary intervention: assessment with cardiac magnetic resonance imaging. J Am Coll Cardiol 36 (5):1557-64. PMID: 11079658
- ↑ Panting JR, Gatehouse PD, Yang GZ, Grothues F, Firmin DN, Collins P et al. (2002) Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Engl J Med 346 (25):1948-53. DOI:10.1056/NEJMoa012369 PMID: 12075055
- ↑ Hundley WG, Hamilton CA, Clarke GD, Hillis LD, Herrington DM, Lange RA et al. (1999) Visualization and functional assessment of proximal and middle left anterior descending coronary stenoses in humans with magnetic resonance imaging. Circulation 99 (25):3248-54. PMID: 10385498
- ↑ Nagel E, Thouet T, Klein C, Schalla S, Bornstedt A, Schnackenburg B et al. (2003) Noninvasive determination of coronary blood flow velocity with cardiovascular magnetic resonance in patients after stent deployment. Circulation 107 (13):1738-43. DOI:10.1161/01.CIR.0000060542.79482.81 PMID: 12665488
- ↑ Langerak SE, Kunz P, Vliegen HW, Jukema JW, Zwinderman AH, Steendijk P et al. (2002) MR flow mapping in coronary artery bypass grafts: a validation study with Doppler flow measurements. Radiology 222 (1):127-35. PMID: 11756716