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{{SI}}
{{Chronic liver disease}}
{{CMG}}
{{CMG}} ; {{AE}} {{ADI}}


==Overview==
==[[Chronic liver disease overview|Overview]]==
'''Chronic liver disease''' is a liver disease of slow process and persisting over a long period of time, resulting in a progressive destruction of the [[liver]].


==Causes==
==[[Chronic liver disease pathophysiology|Pathophysiology]]==


It can refer to:
==[[Chronic liver disease causes|Causes]]==


* [[Cirrhosis]]
==[[Chronic liver disease differential diagnosis|Differentiating Chronic liver disease from other Diseases]]==
* [[Alcoholic liver disease]]
* [[Hepatitis C]]
* [[Hepatitis B]]
* [[Autoimmune hepatitis]]
* [[Liver failure]]
* [[Portal hypertension]]
* [[Hemochromatosis]]
* [[Wilson's disease]]
* [[Gaucher disease]]  
* [[Liver cancer]]
* [[Hepatoma]]
* [[Primary biliary cirrhosis]]
* [[Primary sclerosing cholangitis]]
* [[Sarcoidosis]]
* [[Zellweger syndrome]]


==Risk Factors==
==[[Chronic liver disease epidemiology and demographics|Epidemiology and Demographics]]==


*Health care professionals who are exposed to [[body fluids]] and infected [[blood]]
==[[Chronic liver disease risk factors|Risk Factors]]==


*Individuals who get multiple tattoos and [[body piercing]]
==[[Chronic liver disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
*Certain prescription medications
 
*Excessive [[alcohol]] use
 
*Having high levels of [[fat]] in the blood
 
*Sharing infected needle and syringes
 
*[[Obesity]]
 
*Having unprotected sex and multiple sex partners
 
*Working with toxic chemicals without wearing safety clothes
 
== Natural History, Complications, Prognosis ==
 
'''Complications'''
 
* [[Portal hypertension]]
* [[Hypoalbuminaemia]]
* [[Coagulopathy]]
* [[Hepatopulmonary syndrome]]
* [[Hepatorenal syndrome]]
* [[Encephalopathy]]
* [[Hepatocellular carcinoma]] (also called [[hepatoma]])


==Diagnosis==
==Diagnosis==
===Physical examination===
[[Chronic liver disease history and symptoms|History and Symptoms]] | [[Chronic liver disease physical examination|Physical Examination]] | [[Chronic liver disease laboratory findings|Laboratory Findings]] | [[Chronic liver disease CT|CT]] | [[Chronic liver disease MRI|MRI]] | [[Chronic liver disease echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Chronic liver disease other imaging findings|Other Imaging Findings]] | [[Chronic liver disease other diagnostic studies|Other Diagnostic Studies]]
====Skin====
*Increased pigmentation of the skin
*Tattoos
*[[Scratch mark]]s
==== Eyes ====
*[[Kayser-Fleisher rings]]  


*[[Jaundice]]
==Treatment==
==== Heart ====
[[Chronic liver disease medical therapy|Medical Therapy]] | [[Chronic liver disease surgery|Surgery]] | [[Chronic liver disease prevention|Prevention]] | [[Chronic liver disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Chronic liver disease future or investigational therapies|Future or Investigational Therapies]]
*Signs of [[right heart failure]]
==== Lungs ====
*[[Hyperventilation]]  
==== Abdomen ====
*[[Hepatomegaly]]
*[[Ascites]]  
*[[Spider nevi]] (angiomata)


*[[Caput medusae]]
==Case Studies==
==== Extremities ====
[[Chronic liver disease case study one|Case #1]]
*[[Dupuytren's contracture]]
 
*[[Leukonychia]]
 
*[[Peripheral oedema]]
*[[Bruising]]
 
*[[Nail clubbing|Clubbing]]
 
*[[Palmar erythema]]
==== Neurologic ====
*[[Peripheral neuropathy]]
*[[Cerebellar signs]]
 
*Metabolic Flap/Asterixis
 
*[[Drowsiness]]  
==== Other ====
 
*[[Parotidomegally]]
*[[Gynaecomastia]]
*[[Feminising hair distribution]]
*[[Testicular atrophy]]
*[[Anaemia]]
 
==See Also==


==Related Chapters==
* [[Hepato-biliary diseases]]
* [[Hepato-biliary diseases]]




{{Gastroenterology}}
{{Gastroenterology}}


[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Hepatology]]
[[Category:Disease]]


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Latest revision as of 17:45, 1 June 2016

Chronic liver disease Microchapters

Home

Patient Information

Overview

Pathophysiology

Causes

Differentiating Chronic liver disease from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Chronic liver disease On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chronic liver disease

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Chronic liver disease

CDC on Chronic liver disease

Chronic liver disease in the news

Blogs on Chronic liver disease

Directions to Hospitals Treating Chronic liver disease

Risk calculators and risk factors for Chronic liver disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Pathophysiology

Causes

Differentiating Chronic liver disease from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters


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