Chitin deacetylase

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In enzymology, a chitin deacetylase (EC is an enzyme that catalyzes the chemical reaction

chitin + H2O chitosan + acetate

Thus, the two substrates of this enzyme are chitin and H2O, whereas its two products are chitosan and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chitin amidohydrolase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2IW0.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Araki Y, Ito E (1974). "A pathway of chitosan formation in Mucor rouxii: enzymatic deacetylation of chitin". Biochem. Biophys. Res. Commun. 56: 669&ndash, 75. PMID 4826874.

External links

The CAS registry number for this enzyme class is 56379-60-3.

Gene Ontology (GO) codes