COPB2: Difference between revisions

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Revision as of 09:55, 30 August 2017

Coatomer subunit beta' is a protein that in humans is encoded by the COPB2 gene.^[1]^[2]

Function

The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM]^[2]

Interactions

COPB2 has been shown to interact with:

References

↑ De Baere E, Speleman F, Van Roy N, De Paepe A, Messiaen L (February 1999). "Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization". Cytogenet Cell Genet. 82 (3–4): 226–7. doi:10.1159/000015107. PMID 9858824.
↑ ^2.0 ^2.1 "Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)".
↑ Eugster A, Frigerio G, Dale M, Duden R (August 2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMC 306616. PMID 10921873.
↑ Lowe M, Kreis TE (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. PMID 8940050.
↑ England K, Ashford D, Kidd D, Rumsby M (June 2002). "PKC epsilon is associated with myosin IIA and actin in fibroblasts". Cell. Signal. 14 (6): 529–36. doi:10.1016/s0898-6568(01)00277-7. PMID 11897493.
↑ Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM (September 2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport". Mol. Biol. Cell. 11 (9): 3155–68. doi:10.1091/mbc.11.9.3155. PMC 14982. PMID 10982407.

External links

Human COPB2 genome location and COPB2 gene details page in the UCSC Genome Browser.

Pelham HR, Rothman JE (2000). "The debate about transport in the Golgi--two sides of the same coin?". Cell. 102 (6): 713–9. doi:10.1016/S0092-8674(00)00060-X. PMID 11030615.
Stenbeck G, Harter C, Brecht A, Herrmann D, Lottspeich F, Orci L, Wieland FT (1993). "beta'-COP, a novel subunit of coatomer". EMBO J. 12 (7): 2841–5. PMC 413534. PMID 8334999.
Harrison-Lavoie KJ, Lewis VA, Hynes GM, Collison KS, Nutland E, Willison KR (1993). "A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins". EMBO J. 12 (7): 2847–53. PMC 413536. PMID 8335000.
Lowe M, Kreis TE (1996). "In vitro assembly and disassembly of coatomer". J. Biol. Chem. 270 (52): 31364–71. doi:10.1074/jbc.270.52.31364. PMID 8537409.
Lowe M, Kreis TE (1997). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. PMID 8940050.
Csukai M, Chen CH, De Matteis MA, Mochly-Rosen D (1997). "The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon". J. Biol. Chem. 272 (46): 29200–6. doi:10.1074/jbc.272.46.29200. PMID 9360998.
Eugster A, Frigerio G, Dale M, Duden R (2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMC 306616. PMID 10921873.
Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM (2000). "RGS4 and RGS2 Bind Coatomer and Inhibit COPI Association with Golgi Membranes and Intracellular Transport". Mol. Biol. Cell. 11 (9): 3155–68. doi:10.1091/mbc.11.9.3155. PMC 14982. PMID 10982407.
Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport". J. Biol. Chem. 276 (29): 27480–7. doi:10.1074/jbc.M102786200. PMID 11323436.
Xu Y, Martin S, James DE, Hong W (2003). "GS15 Forms a SNARE Complex with Syntaxin 5, GS28, and Ykt6 and Is Implicated in Traffic in the Early Cisternae of the Golgi Apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961. PMID 12388752.
Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
Rohde HM, Cheong FY, Konrad G, Paiha K, Mayinger P, Boehmelt G (2004). "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex". J. Biol. Chem. 278 (52): 52689–99. doi:10.1074/jbc.M307983200. PMID 14527956.
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells". Mol. Cell. Proteomics. 6 (4): 575–88. doi:10.1074/mcp.M600249-MCP200. PMID 17220478.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[pmid9858824-1] De Baere E, Speleman F, Van Roy N, De Paepe A, Messiaen L (February 1999). "Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization". Cytogenet Cell Genet. 82 (3–4): 226–7. doi:10.1159/000015107. PMID 9858824.

[entrez-2] 2.0 ^2.1 "Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)".

[pmid10921873-3] Eugster A, Frigerio G, Dale M, Duden R (August 2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMC 306616. PMID 10921873.

[pmid8940050-4] Lowe M, Kreis TE (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. PMID 8940050.

[pmid11897493-5] England K, Ashford D, Kidd D, Rumsby M (June 2002). "PKC epsilon is associated with myosin IIA and actin in fibroblasts". Cell. Signal. 14 (6): 529–36. doi:10.1016/s0898-6568(01)00277-7. PMID 11897493.

[pmid10982407-6] Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM (September 2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport". Mol. Biol. Cell. 11 (9): 3155–68. doi:10.1091/mbc.11.9.3155. PMC 14982. PMID 10982407.

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@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Coatomer subunit beta'''' is a [[protein]] that in humans is encoded by the ''COPB2'' [[gene]].<ref name="pmid9858824">{{cite journal | vauthors = De Baere E, Speleman F, Van Roy N, De Paepe A, Messiaen L | title = Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization | journal = Cytogenet Cell Genet | volume = 82 | issue = 3–4 | pages = 226–7 | date = February 1999 | pmid = 9858824 | pmc =  | doi = 10.1159/000015107 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9276| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Coatomer protein complex, subunit beta 2 (beta prime)
- | HGNCid = 2232
- | Symbol = COPB2
- | AltSymbols =; beta'-COP
- | OMIM = 606990
- | ECnumber =
- | Homologene = 3499
- | MGIid = 1354962
- | GeneAtlas_image1 = PBB_GE_COPB2_201098_at_tn.png
- | Function = {{GNF_GO|id=GO:0008565 |text = protein transporter activity}}
- | Component = {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0030126 |text = COPI vesicle coat}}
- | Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0006888 |text = ER to Golgi vesicle-mediated transport}} {{GNF_GO|id=GO:0006890 |text = retrograde vesicle-mediated transport, Golgi to ER}} {{GNF_GO|id=GO:0006891 |text = intra-Golgi vesicle-mediated transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 9276
-    | Hs_Ensembl = ENSG00000184432
-    | Hs_RefseqProtein = NP_004757
-    | Hs_RefseqmRNA = NM_004766
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 3
-    | Hs_GenLoc_start = 140559125
-    | Hs_GenLoc_end = 140591158
-    | Hs_Uniprot = P35606
-    | Mm_EntrezGene = 50797
-    | Mm_Ensembl = ENSMUSG00000032458
-    | Mm_RefseqmRNA = NM_015827
-    | Mm_RefseqProtein = NP_056642
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 9
-    | Mm_GenLoc_start = 98377345
-    | Mm_GenLoc_end = 98397492
-    | Mm_Uniprot = O55029
-  }}
-}}
-'''Coatomer protein complex, subunit beta 2 (beta prime)''', also known as '''COPB2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9276| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM]<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9276| accessdate = }}</ref>
-}}
-==References==
+== Interactions ==
-{{reflist|2}}
-==Further reading==
+COPB2 has been shown to [[Protein-protein interaction|interact]] with:
+* [[COPB1]],<ref name = pmid10921873>{{cite journal | vauthors = Eugster A, Frigerio G, Dale M, Duden R | title = COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP | journal = EMBO J. | volume = 19 | issue = 15 | pages = 3905–17 | date = August 2000 | pmid = 10921873 | pmc = 306616 | doi = 10.1093/emboj/19.15.3905 }}</ref><ref name = pmid8940050>{{cite journal | vauthors = Lowe M, Kreis TE | title = In vivo assembly of coatomer, the COP-I coat precursor | journal = J. Biol. Chem. | volume = 271 | issue = 48 | pages = 30725–30 | date = November 1996 | pmid = 8940050 | doi =  10.1074/jbc.271.48.30725}}</ref>
+* [[PRKCE]],<ref name = pmid11897493>{{cite journal | vauthors = England K, Ashford D, Kidd D, Rumsby M | title = PKC epsilon is associated with myosin IIA and actin in fibroblasts | journal = Cell. Signal. | volume = 14 | issue = 6 | pages = 529–36 | date = June 2002 | pmid = 11897493 | doi =  10.1016/s0898-6568(01)00277-7}}</ref>  and
+* [[RGS4]].<ref name = pmid10982407>{{cite journal | vauthors = Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM | title = RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport | journal = Mol. Biol. Cell | volume = 11 | issue = 9 | pages = 3155–68 | date = September 2000 | pmid = 10982407 | pmc = 14982 | doi =  10.1091/mbc.11.9.3155}}</ref>
+== References ==
+{{reflist}}
+==External links==
+* {{UCSC gene info|COPB2}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Pelham HR, Rothman JE | title = The debate about transport in the Golgi--two sides of the same coin? | journal = Cell | volume = 102 | issue = 6 | pages = 713–9 | year = 2000 | pmid = 11030615 | doi = 10.1016/S0092-8674(00)00060-X }}
-| citations =
+* {{cite journal | vauthors = Stenbeck G, Harter C, Brecht A, Herrmann D, Lottspeich F, Orci L, Wieland FT | title = beta'-COP, a novel subunit of coatomer | journal = EMBO J. | volume = 12 | issue = 7 | pages = 2841–5 | year = 1993 | pmid = 8334999 | pmc = 413534 | doi =  }}
-*{{cite journal  | author=Pelham HR, Rothman JE |title=The debate about transport in the Golgi--two sides of the same coin? |journal=Cell |volume=102 |issue= 6 |pages= 713-9 |year= 2000 |pmid= 11030615 |doi=  }}
+* {{cite journal | vauthors = Harrison-Lavoie KJ, Lewis VA, Hynes GM, Collison KS, Nutland E, Willison KR | title = A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins | journal = EMBO J. | volume = 12 | issue = 7 | pages = 2847–53 | year = 1993 | pmid = 8335000 | pmc = 413536 | doi =  }}
-*{{cite journal  | author=Stenbeck G, Harter C, Brecht A, ''et al.'' |title=beta'-COP, a novel subunit of coatomer. |journal=EMBO J. |volume=12 |issue= 7 |pages= 2841-5 |year= 1993 |pmid= 8334999 |doi=  }}
+* {{cite journal | vauthors = Lowe M, Kreis TE | title = In vitro assembly and disassembly of coatomer | journal = J. Biol. Chem. | volume = 270 | issue = 52 | pages = 31364–71 | year = 1996 | pmid = 8537409 | doi = 10.1074/jbc.270.52.31364 }}
-*{{cite journal  | author=Harrison-Lavoie KJ, Lewis VA, Hynes GM, ''et al.'' |title=A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins. |journal=EMBO J. |volume=12 |issue= 7 |pages= 2847-53 |year= 1993 |pmid= 8335000 |doi=  }}
+* {{cite journal | vauthors = Lowe M, Kreis TE | title = In vivo assembly of coatomer, the COP-I coat precursor | journal = J. Biol. Chem. | volume = 271 | issue = 48 | pages = 30725–30 | year = 1997 | pmid = 8940050 | doi = 10.1074/jbc.271.48.30725 }}
-*{{cite journal  | author=Lowe M, Kreis TE |title=In vitro assembly and disassembly of coatomer. |journal=J. Biol. Chem. |volume=270 |issue= 52 |pages= 31364-71 |year= 1996 |pmid= 8537409 |doi=  }}
+* {{cite journal | vauthors = Csukai M, Chen CH, De Matteis MA, Mochly-Rosen D | title = The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon | journal = J. Biol. Chem. | volume = 272 | issue = 46 | pages = 29200–6 | year = 1997 | pmid = 9360998 | doi = 10.1074/jbc.272.46.29200 }}
-*{{cite journal  | author=Lowe M, Kreis TE |title=In vivo assembly of coatomer, the COP-I coat precursor. |journal=J. Biol. Chem. |volume=271 |issue= 48 |pages= 30725-30 |year= 1997 |pmid= 8940050 |doi=  }}
+* {{cite journal | vauthors = Eugster A, Frigerio G, Dale M, Duden R | title = COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP | journal = EMBO J. | volume = 19 | issue = 15 | pages = 3905–17 | year = 2000 | pmid = 10921873 | pmc = 306616 | doi = 10.1093/emboj/19.15.3905 }}
-*{{cite journal  | author=Csukai M, Chen CH, De Matteis MA, Mochly-Rosen D |title=The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. |journal=J. Biol. Chem. |volume=272 |issue= 46 |pages= 29200-6 |year= 1997 |pmid= 9360998 |doi=  }}
+* {{cite journal | vauthors = Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM | title = RGS4 and RGS2 Bind Coatomer and Inhibit COPI Association with Golgi Membranes and Intracellular Transport | journal = Mol. Biol. Cell | volume = 11 | issue = 9 | pages = 3155–68 | year = 2000 | pmid = 10982407 | pmc = 14982 | doi = 10.1091/mbc.11.9.3155 }}
-*{{cite journal  | author=De Baere E, Speleman F, Van Roy N, ''et al.'' |title=Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=82 |issue= 3-4 |pages= 226-7 |year= 1999 |pmid= 9858824 |doi=  }}
+* {{cite journal | vauthors = Zhang T, Hong W | title = Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport | journal = J. Biol. Chem. | volume = 276 | issue = 29 | pages = 27480–7 | year = 2001 | pmid = 11323436 | doi = 10.1074/jbc.M102786200 }}
-*{{cite journal  | author=Eugster A, Frigerio G, Dale M, Duden R |title=COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP. |journal=EMBO J. |volume=19 |issue= 15 |pages= 3905-17 |year= 2000 |pmid= 10921873 |doi= 10.1093/emboj/19.15.3905 }}
+* {{cite journal | vauthors = Xu Y, Martin S, James DE, Hong W | title = GS15 Forms a SNARE Complex with Syntaxin 5, GS28, and Ykt6 and Is Implicated in Traffic in the Early Cisternae of the Golgi Apparatus | journal = Mol. Biol. Cell | volume = 13 | issue = 10 | pages = 3493–507 | year = 2003 | pmid = 12388752 | pmc = 129961 | doi = 10.1091/mbc.E02-01-0004 }}
-*{{cite journal  | author=Sullivan BM, Harrison-Lavoie KJ, Marshansky V, ''et al.'' |title=RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. |journal=Mol. Biol. Cell |volume=11 |issue= 9 |pages= 3155-68 |year= 2000 |pmid= 10982407 |doi=  }}
+* {{cite journal | vauthors = Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J | title = Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides | journal = Nat. Biotechnol. | volume = 21 | issue = 5 | pages = 566–9 | year = 2004 | pmid = 12665801 | doi = 10.1038/nbt810 }}
-*{{cite journal  | author=Zhang T, Hong W |title=Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport. |journal=J. Biol. Chem. |volume=276 |issue= 29 |pages= 27480-7 |year= 2001 |pmid= 11323436 |doi= 10.1074/jbc.M102786200 }}
+* {{cite journal | vauthors = Rohde HM, Cheong FY, Konrad G, Paiha K, Mayinger P, Boehmelt G | title = The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex | journal = J. Biol. Chem. | volume = 278 | issue = 52 | pages = 52689–99 | year = 2004 | pmid = 14527956 | doi = 10.1074/jbc.M307983200 }}
-*{{cite journal  | author=Xu Y, Martin S, James DE, Hong W |title=GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus. |journal=Mol. Biol. Cell |volume=13 |issue= 10 |pages= 3493-507 |year= 2003 |pmid= 12388752 |doi= 10.1091/mbc.E02-01-0004 }}
+* {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nat. Cell Biol. | volume = 6 | issue = 2 | pages = 97–105 | year = 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
-*{{cite journal  | author=Gevaert K, Goethals M, Martens L, ''et al.'' |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
+* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
-*{{cite journal  | author=Rohde HM, Cheong FY, Konrad G, ''et al.'' |title=The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex. |journal=J. Biol. Chem. |volume=278 |issue= 52 |pages= 52689-99 |year= 2004 |pmid= 14527956 |doi= 10.1074/jbc.M307983200 }}
+* {{cite journal | vauthors = Tu LC, Yan X, Hood L, Lin B | title = Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells | journal = Mol. Cell. Proteomics | volume = 6 | issue = 4 | pages = 575–88 | year = 2007 | pmid = 17220478 | doi = 10.1074/mcp.M600249-MCP200 }}
-*{{cite journal  | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
-*{{cite journal  | author=Tu LC, Yan X, Hood L, Lin B |title=Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. |journal=Mol. Cell Proteomics |volume=6 |issue= 4 |pages= 575-88 |year= 2007 |pmid= 17220478 |doi= 10.1074/mcp.M600249-MCP200 }}
-}}
 {{refend}}
-{{protein-stub}}
+{{Vesicular transport proteins}}
-{{WikiDoc Sources}}
+{{gene-3-stub}}

COPB2: Difference between revisions

Revision as of 09:55, 30 August 2017

Contents

Function

Interactions

References

External links

Further reading

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