AP2S1

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.[1][2][3]

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.[3]

References

  1. Winterpacht A, Endele S, Enklaar T, Fuhry M, Zabel B (Mar 1997). "Human CLAPS2 encoding AP17, a small chain of the clathrin-associated protein complex: cDNA cloning and chromosomal assignment to 19q13.2→q13.3". Cytogenet Cell Genet. 75 (2–3): 132–5. doi:10.1159/000134463. PMID 9040778.
  2. Holzmann K, Poltl A, Sauermann G (Nov 1998). "A novel spliced transcript of human CLAPS2 encoding a protein alternative to clathrin adaptor protein AP17". Gene. 220 (1–2): 39–44. doi:10.1016/S0378-1119(98)00406-5. PMID 9767099.
  3. 3.0 3.1 "Entrez Gene: AP2S1 adaptor-related protein complex 2, sigma 1 subunit".

Further reading

External links