Budd-Chiari syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overview

The hallmark of Budd-Chiari syndrome is a triad of right upper quadrant abdominal pain, ascites, and hepatomegaly. Symptoms of Budd-Chiari syndrome include fever, abdominal pain, abdominal distension from ascites, lower extremity edema, jaundice, gastrointestinal bleeding from varices, portal hypertensive gastropathy, hepatic encephalopathy. Patients with subacute or chronic Budd-Chiari syndrome may be asymptomatic.

History and Symptoms

History and symptoms of Budd-Chiari syndrome include the following:[1][2][3]

History

The hallmark of Budd-Chiari syndrome is a triad of right upper quadrant abdominal pain, ascites, and hepatomegaly. A positive history of associated risk factors such as myeloproliferative disorders, malignancy, paroxysmal nocturnal hemoglobinuria, antiphospholipid syndrome, factor V Leiden mutation, infections and benign liver lesions, oral contraceptives and pregnancy, hypercoagulable states, Behçet's syndrome, membranous webs may be associated with Budd-Chiari syndrome.

Common symptoms

Less common symptoms

References

  1. Goel RM, Johnston EL, Patel KV, Wong T (2015). "Budd-Chiari syndrome: investigation, treatment and outcomes". Postgrad Med J. 91 (1082): 692–7. doi:10.1136/postgradmedj-2015-133402. PMID 26494427.
  2. Aydinli M, Bayraktar Y (2007). "Budd-Chiari syndrome: etiology, pathogenesis and diagnosis". World J. Gastroenterol. 13 (19): 2693–6. PMC 4147117. PMID 17569137.
  3. Marudanayagam R, Shanmugam V, Gunson B, Mirza DF, Mayer D, Buckels J, Bramhall SR (2009). "Aetiology and outcome of acute liver failure". HPB (Oxford). 11 (5): 429–34. doi:10.1111/j.1477-2574.2009.00086.x. PMC 2742613. PMID 19768148.

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