Brugada syndrome historical perspective: Difference between revisions
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The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. | The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. | ||
Before that the characteristic ECG findings were often mistaken for a [[ | Before that the characteristic ECG findings were often mistaken for a [[right ventricle myocardial infarction]]. In 1953 a publication by Oscher mentioned that despite being mistaken for right ventricular myocardial infarction, the ECG findings were not associated with myocardial ischemia.<ref name="pmid13104407">{{cite journal |author=OSHER HL, WOLFF L |title=Electrocardiographic pattern simulating acute myocardial injury |journal=[[The American Journal of the Medical Sciences]] |volume=226 |issue=5 |pages=541–5 |year=1953 |month=November |pmid=13104407 |doi= |url= |issn= |accessdate=2012-10-13}}</ref> | ||
Although the ECG findings of Brugada syndrome were first reported<ref>Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161</ref> among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers<ref>Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182</ref> recognized it as a distinct clinical entity, causing sudden [[death]] by causing [[ventricular fibrillation]] (a lethal [[arrhythmia]]) in the [[heart]]. | Although the ECG findings of Brugada syndrome were first reported<ref>Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161</ref> among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers<ref>Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182</ref> recognized it as a distinct clinical entity, causing sudden [[death]] by causing [[ventricular fibrillation]] (a lethal [[arrhythmia]]) in the [[heart]]. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death.
Before that the characteristic ECG findings were often mistaken for a right ventricle myocardial infarction. In 1953 a publication by Oscher mentioned that despite being mistaken for right ventricular myocardial infarction, the ECG findings were not associated with myocardial ischemia.[1]
Although the ECG findings of Brugada syndrome were first reported[2] among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers[3] recognized it as a distinct clinical entity, causing sudden death by causing ventricular fibrillation (a lethal arrhythmia) in the heart.
References
- ↑ OSHER HL, WOLFF L (1953). "Electrocardiographic pattern simulating acute myocardial injury". The American Journal of the Medical Sciences. 226 (5): 541–5. PMID 13104407. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161
- ↑ Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182