Breast lumps classification: Difference between revisions
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Breast lumps may be classified according to epithelial hyperplasia into 3 subtypes: non-proliferative, proliferative disease and proliferative disease without atypia. | [[Breast lumps]] may be classified according to [[epithelial]] [[hyperplasia]] into 3 subtypes: non-proliferative, proliferative disease and proliferative disease without [[atypia]]. | ||
Breast lumps may be classified into 3 subtypes based on histological regions: lobular region, ductal region, different origins. | [[Breast lumps]] may be classified into 3 subtypes based on [[histological]] regions: [[lobular]] region, ductal region, different origins. | ||
==Classification== | ==Classification== | ||
'''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]<ref name="pmid16034008">{{cite journal| author=Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al.| title=Benign breast disease and the risk of breast cancer. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 3 | pages= 229-37 | pmid=16034008 | doi=10.1056/NEJMoa044383 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16034008 }} </ref>''' | '''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]<ref name="pmid16034008">{{cite journal| author=Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al.| title=Benign breast disease and the risk of breast cancer. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 3 | pages= 229-37 | pmid=16034008 | doi=10.1056/NEJMoa044383 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16034008 }} </ref>''' | ||
*Approximately 65% of all benign breast disease considered as [[nonproliferative]] (NP)with relative cancer risk of 1.2, 1.4 times: | *Approximately 65% of all benign breast disease considered as [[nonproliferative|non-proliferative]] (NP) with relative cancer risk of 1.2, 1.4 times: | ||
**[[ | **Simple [[cyst]] | ||
**[[Fibrosis]] | **[[Fibrosis]] | ||
** [[Fibroadenoma]] (simple) | ** [[Fibroadenoma]] (simple) | ||
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** [[papilloma]] | ** [[papilloma]] | ||
** Radical scar | ** Radical scar | ||
* Approximately 5% to 8% of the rest regarded to [[ | * Approximately 5% to 8% of the rest regarded to PD with [[atypia]] and relative cancer risk more than 4 times | ||
** Atypical lobar [[hyperplasia]] | ** Atypical lobar [[hyperplasia]] | ||
** [[Lobular]] [[carcinoma]] [[in situ]] | ** [[Lobular]] [[carcinoma]] [[in situ]] | ||
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***[[Lipoma]] | ***[[Lipoma]] | ||
***Liponecrosis | ***Liponecrosis | ||
**Fibrous tissue lesions | **[[Fibrous]] tissue lesions | ||
***Focal [[fibrosis]] | ***Focal [[fibrosis]] | ||
***[[Diabetic]] mastopathy | ***[[Diabetic]] mastopathy | ||
***Pseudoangiomatous stromal [[hyperplasia]] (PASH) | ***Pseudoangiomatous [[stromal]] [[hyperplasia]] (PASH) | ||
***Myofibroblastoma | ***Myofibroblastoma | ||
**Vascular origin | **[[Vascular]] origin | ||
***[[Hemangioma]] | ***[[Hemangioma]] | ||
**Inflammatory origin | **[[Inflammatory]] origin | ||
***[[Mastitis]]/[[abscess]] | ***[[Mastitis]]/[[abscess]] | ||
***[[Tuberculosis]] and [[sarcoidosis]] | ***[[Tuberculosis]] and [[sarcoidosis]] | ||
***Foreign body [[granuloma]] and siliconoma | ***Foreign body [[granuloma]] and siliconoma | ||
**Lymph node origin | **Lymph node origin | ||
***Inflammatory lymph nodes | ***[[Inflammatory]] [[lymph nodes]] | ||
==References== | ==References== | ||
Revision as of 17:56, 21 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Breast lumps may be classified according to epithelial hyperplasia into 3 subtypes: non-proliferative, proliferative disease and proliferative disease without atypia.
Breast lumps may be classified into 3 subtypes based on histological regions: lobular region, ductal region, different origins.
Classification
Classification of breast lumps based on epithelial hyperplasia[1]
- Approximately 65% of all benign breast disease considered as non-proliferative (NP) with relative cancer risk of 1.2, 1.4 times:
- Simple cyst
- Fibrosis
- Fibroadenoma (simple)
- Columnar alteration (Simple)
- Apocrine metaplasia (simple)
- Mild ductal hyperplasia
- Approximately 30% of total are classified as (PD) with relative cancer risk of 1.7, 2.1 times
- Usual ductal hyperplasia
- Sclerosing adenosis
- Columnar hyperplasia
- papilloma
- Radical scar
- Approximately 5% to 8% of the rest regarded to PD with atypia and relative cancer risk more than 4 times
- Atypical lobar hyperplasia
- Lobular carcinoma in situ
- Atypical ductal hyperplasia
- Unclear risk
Classification of benign breast lesion regarding to histologist region:[2]
- Terminal and lobular ducts
- Acinar distention
- Intralobular connective tissue proliferation
- Sclerosing adenosis
- Fibroadenoma
- Phyllodes tumor
- Hamartoma
- Epithelial changes in terminal duct lobular units (TDLU)
- Apocrine metaplasia
- Ductal and lobular hyperplasia, usual and typical
- Papillomatosis
- Intracystic papilloma
- Ductal system
- Lesion of different origin
- Fatty tissue lesion
- Lipoma
- Liponecrosis
- Fibrous tissue lesions
- Focal fibrosis
- Diabetic mastopathy
- Pseudoangiomatous stromal hyperplasia (PASH)
- Myofibroblastoma
- Vascular origin
- Inflammatory origin
- Mastitis/abscess
- Tuberculosis and sarcoidosis
- Foreign body granuloma and siliconoma
- Lymph node origin
- Fatty tissue lesion
References
- ↑ Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K; et al. (2005). "Benign breast disease and the risk of breast cancer". N Engl J Med. 353 (3): 229–37. doi:10.1056/NEJMoa044383. PMID 16034008.
- ↑ Lanyi, M (2003). Mammography : diagnosis and pathological analysis. Berlin New York: Springer-Verlag. ISBN 9783540441137.