Atypia
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Ongoing Trials on Atypia at Clinical Trials.gov Clinical Trials on Atypia at Google
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US National Guidelines Clearinghouse on Atypia
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Directions to Hospitals Treating Atypia Risk calculators and risk factors for Atypia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
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Overview
Atypia is a clinical term for abnormality in a cell. The term is medical jargon for an atypical cell. It may or may not be a precancerous indication associated with later malignancy, but the level of appropriate concern is highly dependent on the context with which it is diagnosed.
Atypia can be caused by an infection or irritation if diagnosed in a Pap smear, for example. In the uterus it is more likely to be precancerous.
The term atypia is also used dermatoligically and can be a precursor to melanoma.
A dermatological pathology report may show normal (junctional, compound, or intradermal) nevi, various levels of atypia (slight, moderate, severe), or melanoma. Atypia in this context is a precursor to melanoma, but is not yet melanoma.
If a mole shows slight or moderate atypia and margins are clear, no further treatment is typically needed. It would be wise to re-examine if pigmentation recurs after excision. If a mole shows slight or moderate atypia and margins are not clear, it is typical to re-excise or re-shave to get around the lesion.
If a mole shows marked or severe atypia or any degree of pathologist's concern for melanoma, it would be wise to seek professionals for further evaluation.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
