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'''Extravascular haemolysis'''<br>
'''Extravascular haemolysis'''<br>
Red Blood Cells that are coated with antibodies are specifically recognised in the [[reticuloendothelial system]] and destroyed by [[macrophages]].
Red Blood Cells that are coated with antibodies are specifically recognised in the [[reticuloendothelial system]] and destroyed by [[macrophages]].
===Subtypes===
*'''[[Warm antibody autoimmune hemolytic anemia]]'''
:*Idiopathic
:*[[Systemic lupus erythematosus]]
:*[[Evans' syndrome]] (antiplatelet antibodies and haemolytic antibodies)
:*[[Chronic lymphocytic leukemia]]
:*Drugs ([[methyldopa]])
*'''Cold antibody autoimmune hemolytic anemia'''
:*[[Idiopathic cold hemagglutinin syndrome]]
:*[[Infectious mononucleosis]]
:*[[Paroxysmal cold hemoglobinuria]] (rare)
:*[[Lymphoma]]
*'''Mixed-type autoimmune hemolytic anemia'''


==References==
==References==

Revision as of 15:49, 21 September 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S

Overview

Classification

Haemolysis can be intravascular or extravascular.

Intravascular haemolysis
Red blood cell lysis occurs in the circulation as a result of activation of the complement system cascade.

Extravascular haemolysis
Red Blood Cells that are coated with antibodies are specifically recognised in the reticuloendothelial system and destroyed by macrophages.

Subtypes

  • Cold antibody autoimmune hemolytic anemia
  • Mixed-type autoimmune hemolytic anemia

References

Template:Hematology


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