Autoimmune hemolytic anemia classification: Difference between revisions

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*Idiopathic
*Idiopathic
*[[Systemic lupus erythematosus]]
*[[Systemic lupus erythematosus]]
*[[Evans' syndrome]]
*[[Evans' syndrome]]<ref name="pmid28292089">{{cite journal| author=Bechir A, Haifa R, Nesrine BS, Emna B, Senda M, Asma A et al.| title=Multiple myeloma associated with an Evan's syndrome. | journal=Pan Afr Med J | year= 2016 | volume= 25 | issue=  | pages= 127 | pmid=28292089 | doi=10.11604/pamj.2016.25.127.10750 | pmc=5325491 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28292089  }} </ref>
*[[Chronic lymphocytic leukemia]]
*[[Chronic lymphocytic leukemia]]
*[[Non-Hodgkin lymphoma]]
*[[Non-Hodgkin lymphoma]]
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*Destruction by macrophages
*Destruction by macrophages
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Cold agglutinin disease]]
*[[Cold agglutinin disease]]<ref name="pmid24143001">{{cite journal| author=Randen U, Trøen G, Tierens A, Steen C, Warsame A, Beiske K et al.| title=Primary cold agglutinin-associated lymphoproliferative disease: a B-cell lymphoma of the bone marrow distinct from lymphoplasmacytic lymphoma. | journal=Haematologica | year= 2014 | volume= 99 | issue= 3 | pages= 497-504 | pmid=24143001 | doi=10.3324/haematol.2013.091702 | pmc=3943313 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24143001  }} </ref>
*[[Paroxysmal cold hemoglobinuria]]
*[[Paroxysmal cold hemoglobinuria]]<ref name="pmid18747599">{{cite journal| author=Moncrieff RE| title=Paroxysmal cold hemoglobinuria-1975. | journal=West J Med | year= 1975 | volume= 123 | issue= 6 | pages= 477 | pmid=18747599 | doi= | pmc=1130418 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18747599  }} </ref>
*[[Mycoplasma infection]]
*[[Mycoplasma infection]]<ref name="pmid26696800">{{cite journal| author=Packman CH| title=The Clinical Pictures of Autoimmune Hemolytic Anemia. | journal=Transfus Med Hemother | year= 2015 | volume= 42 | issue= 5 | pages= 317-24 | pmid=26696800 | doi=10.1159/000440656 | pmc=4678314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26696800  }} </ref>
*[[Malignancy]]
*[[Malignancy]]
|-
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Revision as of 16:48, 12 April 2018

Autoimmune hemolytic anemia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S; Shyam Patel [2]

Overview

Classification

Category Features Subtypes

Warm-antibody type

  • Accounts for ~75% of cases of autoimmune hemolytic anemia
  • Due to IgG autoantibody
  • Binding occurs optimally at 37 degrees Celsius
  • Extravascular hemolysis (reticuloendothelial system)

Cold-antibody type

  • Accounts for ~25% of cases of autoimmune hemolytic anemia
  • Due to IgM autoantibody
  • Binding occurs optimally at 4 degrees Celsius
  • Intravascular hemolysis
  • Recognition by the reticuloendothelial system
  • Destruction by macrophages

Mixed warm-antibody and cold-antibody type

  • Due to IgM subtype
  • Mixed features
  • Various clinical entities
  • Generally rare

References

  1. Bechir A, Haifa R, Nesrine BS, Emna B, Senda M, Asma A; et al. (2016). "Multiple myeloma associated with an Evan's syndrome". Pan Afr Med J. 25: 127. doi:10.11604/pamj.2016.25.127.10750. PMC 5325491. PMID 28292089.
  2. Randen U, Trøen G, Tierens A, Steen C, Warsame A, Beiske K; et al. (2014). "Primary cold agglutinin-associated lymphoproliferative disease: a B-cell lymphoma of the bone marrow distinct from lymphoplasmacytic lymphoma". Haematologica. 99 (3): 497–504. doi:10.3324/haematol.2013.091702. PMC 3943313. PMID 24143001.
  3. Moncrieff RE (1975). "Paroxysmal cold hemoglobinuria-1975". West J Med. 123 (6): 477. PMC 1130418. PMID 18747599.
  4. Packman CH (2015). "The Clinical Pictures of Autoimmune Hemolytic Anemia". Transfus Med Hemother. 42 (5): 317–24. doi:10.1159/000440656. PMC 4678314. PMID 26696800.

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