Atopic dermatitis history and symptoms: Difference between revisions

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==Overview==
==Overview==
The most common symptoms of atopic dermatitis include pruritus, distribution of rash on age- specific patters and dry skin. Patients often have personal or family history of asthma or allergic rhinitis. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and atopic disorders.
The most common symptoms of atopic dermatitis include pruritus, distribution of [[rash]] on age- specific patters and [[dry skin]]. Patients often have personal or [[family history]] of [[asthma]] or [[allergic rhinitis]]. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and [[Atopy|atopic disorders]].


==History and Symptoms==
==History and Symptoms==
===History===
===History===
Patients with atopic dermatitis may have a positive history of:<ref name="pmid23712284">{{cite journal |vauthors=Leung DY |title=New insights into atopic dermatitis: role of skin barrier and immune dysregulation |journal=Allergol Int |volume=62 |issue=2 |pages=151–61 |date=June 2013 |pmid=23712284 |doi=10.2332/allergolint.13-RAI-0564 |url=}}</ref><ref name="pmid97349032">{{cite journal |vauthors=Rudikoff D, Lebwohl M |title=Atopic dermatitis |journal=Lancet |volume=351 |issue=9117 |pages=1715–21 |date=June 1998 |pmid=9734903 |doi=10.1016/S0140-6736(97)12082-7 |url=}}</ref>
Patients with atopic dermatitis may have a positive history of:<ref name="pmid23712284">{{cite journal |vauthors=Leung DY |title=New insights into atopic dermatitis: role of skin barrier and immune dysregulation |journal=Allergol Int |volume=62 |issue=2 |pages=151–61 |date=June 2013 |pmid=23712284 |doi=10.2332/allergolint.13-RAI-0564 |url=}}</ref><ref name="pmid97349032">{{cite journal |vauthors=Rudikoff D, Lebwohl M |title=Atopic dermatitis |journal=Lancet |volume=351 |issue=9117 |pages=1715–21 |date=June 1998 |pmid=9734903 |doi=10.1016/S0140-6736(97)12082-7 |url=}}</ref>
*Cutaneous hyper-reactivity to diverse environmental stimuli:
*Cutaneous hyper-reactivity to diverse environmental stimuli including:
**Exposure to food and inhalant allergens
**Exposure to food and inhalant [[allergens]]
**Changes in physical environment (including humidity, pollution etc)
**Changes in physical environment (including [[humidity]], [[pollution]] etc)
**Irritants
**[[Irritants]]
**Microbial infection  
**[[Microbial|Microbial infection]]
**Stress
**[[Stress]]
* Atopic march: Development of clinical signs during childhood from atopic dermatitis to [[asthma]] to [[allergic rhinitis]].<ref name="pmid20674819">{{cite journal |vauthors=Spergel JM |title=From atopic dermatitis to asthma: the atopic march |journal=Ann. Allergy Asthma Immunol. |volume=105 |issue=2 |pages=99–106; quiz 107–9, 117 |date=August 2010 |pmid=20674819 |doi=10.1016/j.anai.2009.10.002 |url=}}</ref><ref name="pmid206748192">{{cite journal |vauthors=Spergel JM |title=From atopic dermatitis to asthma: the atopic march |journal=Ann. Allergy Asthma Immunol. |volume=105 |issue=2 |pages=99–106; quiz 107–9, 117 |date=August 2010 |pmid=20674819 |doi=10.1016/j.anai.2009.10.002 |url=}}</ref><ref name="pmid16935684">{{cite journal |vauthors=Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H |title=Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys |journal=Lancet |volume=368 |issue=9537 |pages=733–43 |date=August 2006 |pmid=16935684 |doi=10.1016/S0140-6736(06)69283-0 |url=}}</ref>
* [[Atopic]] march: Development of clinical signs during childhood from atopic dermatitis to [[asthma]] to [[allergic rhinitis]].<ref name="pmid20674819">{{cite journal |vauthors=Spergel JM |title=From atopic dermatitis to asthma: the atopic march |journal=Ann. Allergy Asthma Immunol. |volume=105 |issue=2 |pages=99–106; quiz 107–9, 117 |date=August 2010 |pmid=20674819 |doi=10.1016/j.anai.2009.10.002 |url=}}</ref><ref name="pmid206748192">{{cite journal |vauthors=Spergel JM |title=From atopic dermatitis to asthma: the atopic march |journal=Ann. Allergy Asthma Immunol. |volume=105 |issue=2 |pages=99–106; quiz 107–9, 117 |date=August 2010 |pmid=20674819 |doi=10.1016/j.anai.2009.10.002 |url=}}</ref><ref name="pmid16935684">{{cite journal |vauthors=Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H |title=Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys |journal=Lancet |volume=368 |issue=9537 |pages=733–43 |date=August 2006 |pmid=16935684 |doi=10.1016/S0140-6736(06)69283-0 |url=}}</ref>
** Cinical features of atopic dermatitis usually occur earlier in life.
** Cinical features of atopic dermatitis usually occur earlier in life.
** Asthma and allergic rhinitis usually occur later on in life.
** [[Asthma]] and [[allergic rhinitis]] usually occur later on in life.


===Common Symptoms===
===Common Symptoms===
Common symptoms of atopic dermatitis include:<ref name="DeleuranVestergaard2014">{{cite journal|last1=Deleuran|first1=M.|last2=Vestergaard|first2=C.|title=Clinical heterogeneity and differential diagnosis of atopic dermatitis|journal=British Journal of Dermatology|volume=170|year=2014|pages=2–6|issn=00070963|doi=10.1111/bjd.12933}}</ref>
Common symptoms of atopic dermatitis include:<ref name="DeleuranVestergaard2014">{{cite journal|last1=Deleuran|first1=M.|last2=Vestergaard|first2=C.|title=Clinical heterogeneity and differential diagnosis of atopic dermatitis|journal=British Journal of Dermatology|volume=170|year=2014|pages=2–6|issn=00070963|doi=10.1111/bjd.12933}}</ref>
*Severe [[pruritus]] : Can cause sleep disturbances in children<ref name="pmid7633537">{{cite journal |vauthors=Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M |title=Sleep disturbances in children with atopic dermatitis |journal=Arch Pediatr Adolesc Med |volume=149 |issue=8 |pages=856–60 |date=August 1995 |pmid=7633537 |doi= |url=}}</ref>
*Severe [[pruritus]] : Can cause [[sleep disturbances]] in children<ref name="pmid7633537">{{cite journal |vauthors=Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M |title=Sleep disturbances in children with atopic dermatitis |journal=Arch Pediatr Adolesc Med |volume=149 |issue=8 |pages=856–60 |date=August 1995 |pmid=7633537 |doi= |url=}}</ref>
*Chronic or relapsing skin lesions
*Chronic or relapsing skin lesions
*Distribution of rash on:
*Distribution of rash on:
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* Nonspecific dermatitis of the hands and feet
* Nonspecific dermatitis of the hands and feet
* [[Food intolerance]]
* [[Food intolerance]]
* Itch when sweating
* [[Itch]] when sweating


==References==
==References==

Revision as of 14:22, 17 October 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]

Overview

The most common symptoms of atopic dermatitis include pruritus, distribution of rash on age- specific patters and dry skin. Patients often have personal or family history of asthma or allergic rhinitis. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and atopic disorders.

History and Symptoms

History

Patients with atopic dermatitis may have a positive history of:[1][2]

Common Symptoms

Common symptoms of atopic dermatitis include:[6]

Less Common Symptoms

Less common symptoms of atopic dermatitis include:[8]

References

  1. Leung DY (June 2013). "New insights into atopic dermatitis: role of skin barrier and immune dysregulation". Allergol Int. 62 (2): 151–61. doi:10.2332/allergolint.13-RAI-0564. PMID 23712284.
  2. Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.
  3. Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
  4. Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
  5. Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H (August 2006). "Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys". Lancet. 368 (9537): 733–43. doi:10.1016/S0140-6736(06)69283-0. PMID 16935684.
  6. Deleuran, M.; Vestergaard, C. (2014). "Clinical heterogeneity and differential diagnosis of atopic dermatitis". British Journal of Dermatology. 170: 2–6. doi:10.1111/bjd.12933. ISSN 0007-0963.
  7. Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M (August 1995). "Sleep disturbances in children with atopic dermatitis". Arch Pediatr Adolesc Med. 149 (8): 856–60. PMID 7633537.
  8. Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.

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