Atopic dermatitis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]
Overview
The most common symptoms of atopic dermatitis include pruritus, distribution of rash in age-specific patterns, and dry skin. Symptoms differ depending on age, stage, race/ethnic group, and geographic location. Patients often have a personal or family history of asthma or allergic rhinitis. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and atopic disorders.
History and Symptoms
History
Patients with atopic dermatitis may have a positive history of:[1][2]
- Cutaneous hyper-reactivity to diverse environmental stimuli including:
- Atopic march: development of clinical signs during childhood from atopic dermatitis to asthma to allergic rhinitis.[3][4][5]
- Clinical features of atopic dermatitis usually occur earlier in life.
- Asthma and allergic rhinitis usually occur later on in life.[6]
Common Symptoms
Common symptoms of atopic dermatitis include:[7][6]
- Severe pruritus: Can cause sleep disturbances in children[8][6]
- Chronic or relapsing skin lesions
- Distribution of rash on:
- Facial and extensor surfaces in infants and young children
- Flexural lichenification in older children and adults
Less Common Symptoms
Less common symptoms of atopic dermatitis include:[9][6]
- Facial pallor
- Dry skin especially in winter)
- Nonspecific dermatitis of the hands and feet
- Food intolerance
- Itch when sweating
- Difficulty sleeping and diminished productivity has also been reported as atopic dermatitis can cause severe pruritus.
References
- ↑ Leung DY (June 2013). "New insights into atopic dermatitis: role of skin barrier and immune dysregulation". Allergol Int. 62 (2): 151–61. doi:10.2332/allergolint.13-RAI-0564. PMID 23712284.
- ↑ Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.
- ↑ Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
- ↑ Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
- ↑ Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H (August 2006). "Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys". Lancet. 368 (9537): 733–43. doi:10.1016/S0140-6736(06)69283-0. PMID 16935684.
- ↑ 6.0 6.1 6.2 6.3 Ständer, Sonja; Ropper, Allan H. (2021). "Atopic Dermatitis". New England Journal of Medicine. 384 (12): 1136–1143. doi:10.1056/NEJMra2023911. ISSN 0028-4793.
- ↑ Deleuran, M.; Vestergaard, C. (2014). "Clinical heterogeneity and differential diagnosis of atopic dermatitis". British Journal of Dermatology. 170: 2–6. doi:10.1111/bjd.12933. ISSN 0007-0963.
- ↑ Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M (August 1995). "Sleep disturbances in children with atopic dermatitis". Arch Pediatr Adolesc Med. 149 (8): 856–60. PMID 7633537.
- ↑ Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.