Arterial and venous thrombosis differences and similarities: Difference between revisions
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More than a century ago, Virchow postulated that a triad of conditions (later called [[Virchow's triad]]) leads to [[Thrombus]] formation. Traditionally, Venous thrombosis has been associated with red blood cell and fibrin rich '''red clot''' while Arterial thrombosis occur on atherosclerotic lesions with active inflammation, and are rich in platelets and give an appearance of '''white clot''' <ref name="pmid15615791">{{cite journal| author=Jerjes-Sanchez C| title=Venous and arterial thrombosis: a continuous spectrum of the same disease? | journal=Eur Heart J | year= 2005 | volume= 26 | issue= 1 | pages= 3-4 | pmid=15615791 | doi=10.1093/eurheartj/ehi041 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15615791 }} </ref>. Furthermore certain studies have indicated the role of platelet in Venous thrombosis<ref name="pmid12356622">{{cite journal| author=Sobieszczyk P, Fishbein MC, Goldhaber SZ| title=Acute pulmonary embolism: don't ignore the platelet. | journal=Circulation | year= 2002 | volume= 106 | issue= 14 | pages= 1748-9 | pmid=12356622 | doi= | pmc= | url= }} </ref>. | More than a century ago, Virchow postulated that a triad of conditions (later called [[Virchow's triad]]) leads to [[Thrombus]] formation. Traditionally, Venous thrombosis has been associated with red blood cell and fibrin rich '''red clot''' while Arterial thrombosis occur on atherosclerotic lesions with active inflammation, and are rich in platelets and give an appearance of '''white clot''' <ref name="pmid15615791">{{cite journal| author=Jerjes-Sanchez C| title=Venous and arterial thrombosis: a continuous spectrum of the same disease? | journal=Eur Heart J | year= 2005 | volume= 26 | issue= 1 | pages= 3-4 | pmid=15615791 | doi=10.1093/eurheartj/ehi041 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15615791 }} </ref>. Furthermore certain studies have indicated the role of platelet in Venous thrombosis<ref name="pmid12356622">{{cite journal| author=Sobieszczyk P, Fishbein MC, Goldhaber SZ| title=Acute pulmonary embolism: don't ignore the platelet. | journal=Circulation | year= 2002 | volume= 106 | issue= 14 | pages= 1748-9 | pmid=12356622 | doi= | pmc= | url= }} </ref>. | ||
According to a study done A recent analysis published in Circulation in 2008 repeated these findings and found | |||
==Similarities== | ==Similarities== | ||
The two vascular complications, venous and arterial thrombosis, share many risk factors such as: | The two vascular complications, venous and arterial thrombosis, share many risk factors such as: | ||
Revision as of 20:30, 16 September 2011
| Arterial and venous thrombosis differences and similarities | |
| ICD-10 | I80-I82 |
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| ICD-9 | 437.6, 453, 671.5, 671.9 |
| MeSH | D013927 |
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Thrombosis Microchapters |
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Site of Thrombosis |
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Differentiating Thrombosis from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editors-in-Chief: Ujjwal Rastogi, MBBS [2]
Overview
More than a century ago, Virchow postulated that a triad of conditions (later called Virchow's triad) leads to Thrombus formation. Traditionally, Venous thrombosis has been associated with red blood cell and fibrin rich red clot while Arterial thrombosis occur on atherosclerotic lesions with active inflammation, and are rich in platelets and give an appearance of white clot [1]. Furthermore certain studies have indicated the role of platelet in Venous thrombosis[2].
According to a study done A recent analysis published in Circulation in 2008 repeated these findings and found
Similarities
The two vascular complications, venous and arterial thrombosis, share many risk factors such as:
- Age
- Obesity
- Diabetes mellitus
- Hypertension
- Hypertriglyceridemia
- Metabolic syndrome.
Furthermore there are many diseases that causes both arterial and venous thrombosis, such as:
- Antiphospholipid antibody syndrome,
- Hyperhomocysteinemia,
- Malignancies,
- Infections,
- Nephrotic Syndrome [3].
- Hormonal treatment,
- Bechet's disease,
- Poplitial artery aneurysm (Large aneurysm can compress the poplitial vein and cause DVT).
References
- ↑ Jerjes-Sanchez C (2005). "Venous and arterial thrombosis: a continuous spectrum of the same disease?". Eur Heart J. 26 (1): 3–4. doi:10.1093/eurheartj/ehi041. PMID 15615791.
- ↑ Sobieszczyk P, Fishbein MC, Goldhaber SZ (2002). "Acute pulmonary embolism: don't ignore the platelet". Circulation. 106 (14): 1748–9. PMID 12356622.
- ↑ Mahmoodi BK, ten Kate MK, Waanders F, Veeger NJ, Brouwer JL, Vogt L; et al. (2008). "High absolute risks and predictors of venous and arterial thromboembolic events in patients with nephrotic syndrome: results from a large retrospective cohort study". Circulation. 117 (2): 224–30. doi:10.1161/CIRCULATIONAHA.107.716951. PMID 18158362.