Acute bronchitis medical therapy: Difference between revisions

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{{Acute bronchitis}}
{{Acute bronchitis}}
{{CMG}}
{{CMG}}{{AE}}{{MehdiP}}


==Overview==
==Overview==
Acute bronchitis may be treated through multiple pharmacologic regimens such as [[antibiotics]] and [[antihistamine]].
There is no need for medical therapy in most of acute bronchitis patients and they only need reassurance and symptomatic therapy. Antibiotics should not be prescribed routinely for patients with acute bronchitis<ref name="pmid15972565">{{cite journal |vauthors=Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I |title=Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial |journal=JAMA |volume=293 |issue=24 |pages=3029–35 |year=2005 |pmid=15972565 |doi=10.1001/jama.293.24.3029 |url=}}</ref><ref name="pmid24585130">{{cite journal |vauthors=Smith SM, Fahey T, Smucny J, Becker LA |title=Antibiotics for acute bronchitis |journal=Cochrane Database Syst Rev |volume= |issue=3 |pages=CD000245 |year=2014 |pmid=24585130 |doi=10.1002/14651858.CD000245.pub3 |url=}}</ref><ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S |year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref><ref name="pmid17108344">{{cite journal |vauthors=Wenzel RP, Fowler AA |title=Clinical practice. Acute bronchitis |journal=N. Engl. J. Med. |volume=355 |issue=20 |pages=2125–30 |year=2006 |pmid=17108344 |doi=10.1056/NEJMcp061493 |url=}}</ref>.
 
==Medical Therapy==
==Antibiotics==
Many of patients may benefit from NSAIDS such as; aspirin and acetaminophen to relief the constitutional symptoms or albuterol if the cough is disturbing<ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S |year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref>.
In most cases, acute bronchitis is caused by [[virus]]es, not [[bacteria]] and it will go away on its own without antibiotics. To treat acute bronchitis that appears to be caused by a bacterial infection, or as a precaution, [[antibiotic]]s may be given.<ref>[http://www.merck.com/mmhe/sec04/ch041/ch041a.html The Merck Manual of Medical Information: Bronchitis]. February 2003.  Accessed [[20 March]] [[2007]].</ref> However, a [[meta-analysis]] found that antibiotics may reduce symptoms by one-half day.<ref name="pmid10403354">{{cite journal |author=Bent S, Saint S, Vittinghoff E, Grady D |title=Antibiotics in acute bronchitis: a meta-analysis |journal=Am. J. Med. |volume=107 |issue=1 |pages=62–7 |year=1999 |pmid=10403354 |doi=}}</ref>
 
==Antihistamines==
Using over-the-counter [[antihistamine]]s may be harmful in the self-treatment of bronchitis.<ref>[http://www.merck.com/mmhe/sec04/ch039/ch039b.html Merck Manual Home Edition: Symptoms and Diagnosis of Lung Disorders: Symptoms]. November 2006. Accessed [[6 October]] [[2007]].</ref>
 
An effect of antihistamines is to thicken mucus secretions. Expelling infected mucus via coughing can be beneficial in recovering from bronchitis. Expulsion of the mucus may be hindered if it is thickened. Antihistamines can help bacteria to persist and multiply in the lungs by increasing its residence time in a warm, moist environment of thickened mucus.
 
Using antihistamines along with an expectorant cough syrup may be doubly harmful: encouraging the production of mucus and then thickening that which is produced. Using an expectorant cough syrup alone might be useful in flushing bacteria from the lungs.  Using an antihistamine along with it works against the intention of using the expectorant.


==References==
==References==

Revision as of 20:37, 12 September 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

There is no need for medical therapy in most of acute bronchitis patients and they only need reassurance and symptomatic therapy. Antibiotics should not be prescribed routinely for patients with acute bronchitis[1][2][3][4].

Medical Therapy

Many of patients may benefit from NSAIDS such as; aspirin and acetaminophen to relief the constitutional symptoms or albuterol if the cough is disturbing[3].

References

  1. Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I (2005). "Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial". JAMA. 293 (24): 3029–35. doi:10.1001/jama.293.24.3029. PMID 15972565.
  2. Smith SM, Fahey T, Smucny J, Becker LA (2014). "Antibiotics for acute bronchitis". Cochrane Database Syst Rev (3): CD000245. doi:10.1002/14651858.CD000245.pub3. PMID 24585130.
  3. 3.0 3.1 Braman SS (2006). "Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines". Chest. 129 (1 Suppl): 95S–103S. doi:10.1378/chest.129.1_suppl.95S. PMID 16428698.
  4. Wenzel RP, Fowler AA (2006). "Clinical practice. Acute bronchitis". N. Engl. J. Med. 355 (20): 2125–30. doi:10.1056/NEJMcp061493. PMID 17108344.


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