Acute bronchitis medical therapy: Difference between revisions

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{{Acute bronchitis}}
{{Acute bronchitis}}
{{CMG}}
{{CMG}}{{AE}}{{MehdiP}}; {{NRM}}


==Overview==
==Overview==
Acute bronchitis may be treated through multiple pharmacologic regimens such as [[antibiotics]] and [[antihistamine]].
There is no need for medical therapy in most of acute bronchitis patients; reassurance and symptomatic therapy are usually sufficient. Antibiotics should '''''not''''' be prescribed routinely for patients with acute bronchitis<ref name="pmid15972565">{{cite journal |vauthors=Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I |title=Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial |journal=JAMA |volume=293 |issue=24 |pages=3029–35 |year=2005 |pmid=15972565 |doi=10.1001/jama.293.24.3029 |url=}}</ref><ref name="pmid24585130">{{cite journal |vauthors=Smith SM, Fahey T, Smucny J, Becker LA |title=Antibiotics for acute bronchitis |journal=Cochrane Database Syst Rev |volume= |issue=3 |pages=CD000245 |year=2014 |pmid=24585130 |doi=10.1002/14651858.CD000245.pub3 |url=}}</ref><ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S |year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref><ref name="pmid17108344">{{cite journal |vauthors=Wenzel RP, Fowler AA |title=Clinical practice. Acute bronchitis |journal=N. Engl. J. Med. |volume=355 |issue=20 |pages=2125–30 |year=2006 |pmid=17108344 |doi=10.1056/NEJMcp061493 |url=}}</ref><ref name="pmid17002029">{{cite journal |vauthors=Wong DM, Blumberg DA, Lowe LG |title=Guidelines for the use of antibiotics in acute upper respiratory tract infections |journal=Am Fam Physician |volume=74 |issue=6 |pages=956–66 |year=2006 |pmid=17002029 |doi= |url=}}</ref>
==Medical Therapy==
Majority of patients may benefit from [[NSAIDs]], such as [[aspirin]] or [[acetaminophen]], to relieve constitutional symptoms and [[albuterol]] if the [[cough]] is disruptive.<ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S
|year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref>


==Antibiotics==
=== Medications ===
In most cases, acute bronchitis is caused by [[virus]]es, not [[bacteria]] and it will go away on its own without antibiotics. To treat acute bronchitis that appears to be caused by a bacterial infection, or as a precaution, [[antibiotic]]s may be given.<ref>[http://www.merck.com/mmhe/sec04/ch041/ch041a.html The Merck Manual of Medical Information: Bronchitis].  February 2003.  Accessed [[20 March]] [[2007]].</ref> However, a [[meta-analysis]] found that antibiotics may reduce symptoms by one-half day.<ref name="pmid10403354">{{cite journal |author=Bent S, Saint S, Vittinghoff E, Grady D |title=Antibiotics in acute bronchitis: a meta-analysis |journal=Am. J. Med. |volume=107 |issue=1 |pages=62–7 |year=1999 |pmid=10403354 |doi=}}</ref>
*[[Albuterol]]: alleviation of wheezing and symptoms of airway obstruction
*[[Antitussive|Antitussives]]: [[codeine]] or [[dextromethorphan]] for <ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S |year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref>
*[[NSAIDs]]: alleviation of constitutional symptoms, such as [[myalgia]] and [[fever]]


==Antihistamines==
Antibiotics '''''SHOULD NOT''''' be prescribed unless there is strong evidence of bacterial infection, especially in [[Comorbidity|comorbid]] conditions, such as chronic [[Heart disease|heart]] or [[lung diseases]] and [[immunocompromised]] or [[Neuromuscular disease|neuromuscular diseases]].<ref name="pmid15972565">{{cite journal |vauthors=Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I |title=Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial |journal=JAMA |volume=293 |issue=24 |pages=3029–35 |year=2005 |pmid=15972565 |doi=10.1001/jama.293.24.3029 |url=}}</ref><ref name="pmid24585130">{{cite journal |vauthors=Smith SM, Fahey T, Smucny J, Becker LA |title=Antibiotics for acute bronchitis |journal=Cochrane Database Syst Rev |volume= |issue=3 |pages=CD000245 |year=2014 |pmid=24585130 |doi=10.1002/14651858.CD000245.pub3 |url=}}</ref><ref name="pmid16428698">{{cite journal |vauthors=Braman SS |title=Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines |journal=Chest |volume=129 |issue=1 Suppl |pages=95S–103S |year=2006 |pmid=16428698 |doi=10.1378/chest.129.1_suppl.95S |url=}}</ref><ref name="pmid17108344">{{cite journal |vauthors=Wenzel RP, Fowler AA |title=Clinical practice. Acute bronchitis |journal=N. Engl. J. Med. |volume=355 |issue=20 |pages=2125–30 |year=2006 |pmid=17108344 |doi=10.1056/NEJMcp061493 |url=}}</ref><ref name="pmid17002029">{{cite journal |vauthors=Wong DM, Blumberg DA, Lowe LG |title=Guidelines for the use of antibiotics in acute upper respiratory tract infections |journal=Am Fam Physician |volume=74 |issue=6 |pages=956–66 |year=2006 |pmid=17002029 |doi= |url=}}</ref>
Using over-the-counter [[antihistamine]]s may be harmful in the self-treatment of bronchitis.<ref>[http://www.merck.com/mmhe/sec04/ch039/ch039b.html Merck Manual Home Edition: Symptoms and Diagnosis of Lung Disorders: Symptoms]. November 2006. Accessed [[6 October]] [[2007]].</ref>
 
An effect of antihistamines is to thicken mucus secretions. Expelling infected mucus via coughing can be beneficial in recovering from bronchitis. Expulsion of the mucus may be hindered if it is thickened. Antihistamines can help bacteria to persist and multiply in the lungs by increasing its residence time in a warm, moist environment of thickened mucus.
 
Using antihistamines along with an expectorant cough syrup may be doubly harmful: encouraging the production of mucus and then thickening that which is produced. Using an expectorant cough syrup alone might be useful in flushing bacteria from the lungs. Using an antihistamine along with it works against the intention of using the expectorant.


==References==
==References==
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[[Category:Inflammations]]
[[Category:Pulmonology]]
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[[Category:General practice]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Overview complete]]
[[Category:Surgery]]
[[Category:Up-To-Date]]
[[Category:Emergency medicine]]
[[Category:Infectious disease]]

Latest revision as of 20:15, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]; Nate Michalak, B.A.

Overview

There is no need for medical therapy in most of acute bronchitis patients; reassurance and symptomatic therapy are usually sufficient. Antibiotics should not be prescribed routinely for patients with acute bronchitis[1][2][3][4][5]

Medical Therapy

Majority of patients may benefit from NSAIDs, such as aspirin or acetaminophen, to relieve constitutional symptoms and albuterol if the cough is disruptive.[3]

Medications

Antibiotics SHOULD NOT be prescribed unless there is strong evidence of bacterial infection, especially in comorbid conditions, such as chronic heart or lung diseases and immunocompromised or neuromuscular diseases.[1][2][3][4][5]

References

  1. 1.0 1.1 Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I (2005). "Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial". JAMA. 293 (24): 3029–35. doi:10.1001/jama.293.24.3029. PMID 15972565.
  2. 2.0 2.1 Smith SM, Fahey T, Smucny J, Becker LA (2014). "Antibiotics for acute bronchitis". Cochrane Database Syst Rev (3): CD000245. doi:10.1002/14651858.CD000245.pub3. PMID 24585130.
  3. 3.0 3.1 3.2 3.3 Braman SS (2006). "Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines". Chest. 129 (1 Suppl): 95S–103S. doi:10.1378/chest.129.1_suppl.95S. PMID 16428698.
  4. 4.0 4.1 Wenzel RP, Fowler AA (2006). "Clinical practice. Acute bronchitis". N. Engl. J. Med. 355 (20): 2125–30. doi:10.1056/NEJMcp061493. PMID 17108344.
  5. 5.0 5.1 Wong DM, Blumberg DA, Lowe LG (2006). "Guidelines for the use of antibiotics in acute upper respiratory tract infections". Am Fam Physician. 74 (6): 956–66. PMID 17002029.


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