Acromegaly history and symptoms: Difference between revisions
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* Increased palmar sweating and [[sebum]] production over the face ([[seborrhea]]) are clinical indicators of active growth hormone (GH) producing pituitary tumours. These symptoms can also be used to monitor the activity of the tumour after surgery although biochemical monitoring is confirmatory. | * Increased palmar sweating and [[sebum]] production over the face ([[seborrhea]]) are clinical indicators of active growth hormone (GH) producing pituitary tumours. These symptoms can also be used to monitor the activity of the tumour after surgery although biochemical monitoring is confirmatory. | ||
(Image courtesy of Charlie Goldberg, M.D., UCSD School of Medicine and VA Medical Center, San Diego, California) | |||
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Image:acromegaly1.jpg|Facial changes secondary to elevated growth hormone levels. Note in particular prominent supra-orbital ridge, jaw, and generally enlarged facial features. | |||
Image:Acromegaly3.jpg|Markedly enlarged hand resulting from excess growth hormone. For reference purposes, the comparison hand is size 6 1/2. | |||
Image:acromegaly4.jpg|Facial changes secondary to elevated growth hormone levels. Note in particular prominent supra-orbital ridge, jaw, and generally enlarged facial features. | |||
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==References== | ==References== | ||
Revision as of 15:57, 18 January 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Symptoms
Features that result from high level of hGH or expanding tumor include:
- Soft tissue swelling of the hands and feet
- Brow and lower jaw protrusion
- Enlarging hands
- Enlarging feet
- Arthritis and carpal tunnel syndrome
- Teeth spacing increase
- Macroglossia [enlarged tongue]
- Heart failure
- Kidney failure
- Compression of the optic chiasm leading to loss of vision in the outer visual fields (typically bitemporal hemianopia)
- Headache
- Diabetes mellitus
- Hypertension
- Enlarging heart
- Increased palmar sweating and sebum production over the face (seborrhea) are clinical indicators of active growth hormone (GH) producing pituitary tumours. These symptoms can also be used to monitor the activity of the tumour after surgery although biochemical monitoring is confirmatory.
(Image courtesy of Charlie Goldberg, M.D., UCSD School of Medicine and VA Medical Center, San Diego, California)
-
Facial changes secondary to elevated growth hormone levels. Note in particular prominent supra-orbital ridge, jaw, and generally enlarged facial features.
-
Markedly enlarged hand resulting from excess growth hormone. For reference purposes, the comparison hand is size 6 1/2.
-
Facial changes secondary to elevated growth hormone levels. Note in particular prominent supra-orbital ridge, jaw, and generally enlarged facial features.
References
bg:Акромегалия cs:Akromegalie de:Akromegalie gl:Acromegalia it:Acromegalia he:אקרומגליה nl:Acromegalie no:Akromegali sq:Akromegalia sk:Akromegália sr:Акромегалија fi:Akromegalia sv:Akromegali uk:Акромегалія