17 alpha-hydroxylase deficiency natural history, complications and prognosis: Difference between revisions
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{{ | {{17 alpha-hydroxylase deficiency}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
If left untreated, patients with | If left untreated, patients with 17 alpha-hydroxylase deficiency may progress to develop [[malignant hypertension]]. Common complications of 17 alpha-hydroxylase deficiency include muscle weakness, [[metabolic alkalosis]], and [[azoospermia]]. Prognosis is generally good with treatment. | ||
==Natural History== | ==Natural History== | ||
If left untreated, patients with | If left untreated, patients with 17 alpha-hydroxylase deficiency may progress to develop malignant hypertension. | ||
==Complications== | ==Complications== | ||
===Complications of Hypertension=== | ===Complications of Hypertension=== | ||
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* [[Stroke]] | * [[Stroke]] | ||
===Complications of Hypokalemia=== | ===Complications of Hypokalemia=== | ||
* Muscle weakness | * [[Muscle weakness]] | ||
* [[Metabolic alkalosis]] | * [[Metabolic alkalosis]] | ||
* [[Paralytic ileus]] | * [[Paralytic ileus]] | ||
===Other Complications=== | ===Other Complications=== | ||
* [[Infertility]] | * [[Infertility]] | ||
==Prognosis== | ==Prognosis== | ||
*The prognosis of | *The prognosis of 17 alpha-hydroxylase deficiency is generally good or excellent. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 16:16, 7 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
If left untreated, patients with 17 alpha-hydroxylase deficiency may progress to develop malignant hypertension. Common complications of 17 alpha-hydroxylase deficiency include muscle weakness, metabolic alkalosis, and azoospermia. Prognosis is generally good with treatment.
Natural History
If left untreated, patients with 17 alpha-hydroxylase deficiency may progress to develop malignant hypertension.
Complications
Complications of Hypertension
- Vascular hemorrhage
- Renal insufficiency
- Left ventricular hypertrophy
- Hypertensive retinopathy
- Stroke
Complications of Hypokalemia
Other Complications
Prognosis
- The prognosis of 17 alpha-hydroxylase deficiency is generally good or excellent.