Patent foramen ovale epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]

Overview

Approximately 1 in every three normal adults have a patent foramen ovale.[1] The incidence decreases with increasing age, but the size increases with age. There is no difference in the incidence associated with gender.

Epidemiology and Demographics

The incidence of Patent foramen ovale has been found to be approximately 30% in different studies.[1]

Age

The incidence of a patent foramen ovale varies with age:[2]

  • 0-30 years: 34.3%
  • 40-80 years: 25.4%
  • 90+ years: 20.2%

PFO size increases with age, from a mean of approximately 3mm in the first decade to approximately 6 mm in the 10th decade of life. [2]

Size

The size of patent foramen ovale might ranges from 1 to 19 mm. However, in most cases it has been found to vary from 1 to 10 mm in diameter. PFO size increases with age, from a mean of approximately 3mm in the first decade to approximately 6 mm in the 10th decade of life. [2]

Gender

There is no significant difference in size or incidence associated with gender.

References

  1. 1.0 1.1 Meissner I, Whisnant JP, Khandheria BK, Spittell PC, O'Fallon WM, Pascoe RD; et al. (1999). "Prevalence of potential risk factors for stroke assessed by transesophageal echocardiography and carotid ultrasonography: the SPARC study. Stroke Prevention: Assessment of Risk in a Community". Mayo Clin Proc. 74 (9): 862–9. PMID 10488786.
  2. 2.0 2.1 2.2 Hagen PT, Scholz DG, Edwards WD (1984). "Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts". Mayo Clin Proc. 59 (1): 17–20. PMID 6694427.


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