Hypogonadism history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

History and symptoms

History is important in diagnosis of hypogonadism in both males and females. The onset of the symptoms and previous congenital gonadal anomalies should be known.

For both males and females:
- History is important to know if there was any gonadal abnormality since birth or not. The onset of puberty should also be known.
- Family history of delay of growth and development is also important.
For males:
- History of any causes of testicular failure as radiation to testes, chemotherapy or drugs decreasing testosterone secretion.
For females:
- Menstrual history is important and the date of menarche.
- History of increased androgen secretion as ance and hirsutism.

Common symptoms in males

Symptoms of hypogonadism depends on the onset of the disease whether before puberty or after. In this table, the common symptoms of hypogonadism in both periods are enlisted.^[1]^[2]

Pre-pubertal	Post-pubertal (Adult)
Delayed puberty and loss of sexual characters: No beard Failure of voice deepening Small testes No muscle mass gaining	Decrease of libido Decreased erections Erectile dysfunction Decreased size of testes Sweating Breast enlargement Muscle loss and decreased bone density Infertility Loss of body hair

Less common symptoms

References

↑ Khera M, Broderick GA, Carson CC, Dobs AS, Faraday MM, Goldstein I; et al. (2016). "Adult-Onset Hypogonadism". Mayo Clin Proc. 91 (7): 908–26. doi:10.1016/j.mayocp.2016.04.022. PMID 27343020.
↑ Basaria S (2014). "Male hypogonadism". Lancet. 383 (9924): 1250–63. doi:10.1016/S0140-6736(13)61126-5. PMID 24119423.

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[pmid27343020-1] Khera M, Broderick GA, Carson CC, Dobs AS, Faraday MM, Goldstein I; et al. (2016). "Adult-Onset Hypogonadism". Mayo Clin Proc. 91 (7): 908–26. doi:10.1016/j.mayocp.2016.04.022. PMID 27343020.

[pmid24119423-2] Basaria S (2014). "Male hypogonadism". Lancet. 383 (9924): 1250–63. doi:10.1016/S0140-6736(13)61126-5. PMID 24119423.

[1]

[2]