Lung mass biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Biopsy for lung mass may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with lung mass will depend on tumor histology. Common types of lung tissue biopsy for pulmonary mass, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass, include: suspected lung cancer, malignant features (lymph node involvement) .[1][2]

Biopsy

Biopsy for lung mass may be classified into 2 categories:[1]

  • Non-surgical biopsy
  • Bronchoscopy
  • Transthoracic needle biopsy
  • Needle core biopsy
  • Surgical
  • Wedge resection
  • Surgical resection is the preferred biopsy choice for lung mass
  • Indications for biopsy in lung mass, include:[1]
  • Suspected lung cancer
  • Determination of tumor histologic subtype
  • Characterization of genetic mutations
  • Contraindications for biopsy in lung mass, include:[1]
  • Emphysema
  • Bullous disease
  • Chronic respiratory failure
  • Complications for for biopsy in lung mass, include:[1]
  • Pneumothorax
  • Hemothorax

Non-Surgical Biopsy

Bronchoscopy

  • Common bronchoscopy biopsy techniques for lung mass, include:[1][2]
  • Conventional bronchoscopic-guided transbronchial biopsy
  • Bronchoscopic-transbronchial needle aspiration
  • Endobronchial ultrasound-guided sheath transbronchial biopsy
  • Endobronchial ultrasound-guided transbronchial needle aspiration
  • Indications for bronchoscopy in lung mass, include:[2]
  • Central nodules
  • Large lesions
  • No fitness for surgery
  • Nodules close to the patent airways
  • Patients were the risk of complications from any other biopsy is high

Transthoracic needle biopsy

  • Usually followed by CT guidance
  • Indications for transthoracic needle biopsy in pulmonary nodule, include:[2]
  • Peripheral nodules
  • Nodules close to the chest wall
  • No fitness for surgery



References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Herman M, Galanter M, Lifshutz H (1991). "Combined substance abuse and psychiatric disorders in homeless and domiciled patients". Am J Drug Alcohol Abuse. 17 (4): 415–22. PMID 1746503.
  2. 2.0 2.1 2.2 2.3 Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM (2004). "Percutaneous biopsy in evaluation of lung nodules". JSLS. 8 (3): 213–6. PMC 3016799. PMID 15347106.