Cretinism causes

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Cretinism Microchapters

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Causes

Differentiating Cretinism from other Diseases

Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Cretinism may be caused by congenital causes like thyroid dysgenesis and ectopic thyroid gland. Cretinism may be caused by other causes like antithyroid medications and iodine deficiency.

Causes

Primary cretinism

Common Causes

Primary Cretinism may be caused by:[1][2]

Secondary (central) hypothyroidism

Central hypothyroidism is caused by:[3]

Genetic Causes

Causes in Alphabetical Order

List the causes of the disease in alphabetical order.

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3

References

  1. Persani L, Calebiro D, Cordella D, Weber G, Gelmini G, Libri D; et al. (2010). "Genetics and phenomics of hypothyroidism due to TSH resistance". Mol Cell Endocrinol. 322 (1–2): 72–82. doi:10.1016/j.mce.2010.01.008. PMID 20083154.
  2. Wassner AJ (2017). "Pediatric Hypothyroidism: Diagnosis and Treatment". Paediatr Drugs. 19 (4): 291–301. doi:10.1007/s40272-017-0238-0. PMID 28534114.
  3. Kempers MJ, van Tijn DA, van Trotsenburg AS, de Vijlder JJ, Wiedijk BM, Vulsma T (2003). "Central congenital hypothyroidism due to gestational hyperthyroidism: detection where prevention failed". J Clin Endocrinol Metab. 88 (12): 5851–7. doi:10.1210/jc.2003-030665. PMID 14671180.
  4. Narumi S, Muroya K, Asakura Y, Aachi M, Hasegawa T (2011). "Molecular basis of thyroid dyshormonogenesis: genetic screening in population-based Japanese patients". J Clin Endocrinol Metab. 96 (11): E1838–42. doi:10.1210/jc.2011-1573. PMID 21900383.
  5. Ohye H, Fukata S, Hishinuma A, Kudo T, Nishihara E, Ito M; et al. (2008). "A novel homozygous missense mutation of the dual oxidase 2 (DUOX2) gene in an adult patient with large goiter". Thyroid. 18 (5): 561–6. doi:10.1089/thy.2007.0258. PMID 18426362.

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