Hurler syndrome history and symptoms: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 5: Line 5:
Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.


==History and Symptoms==
==Overview==
Affected children may be quite large at [[childbirth|birth]] and appear normal but may have inguinal (in the groin) or umbilical (where the [[umbilical cord]] passes through the [[abdomen]]) hernias. Growth in height may be initially faster than normal, then begins to slow before the end of the first year and often ends around age 3. Many children develop a short body trunk and a maximum stature of less than 4 feet. Distinct facial features (including flat face, depressed nasal bridge, and bulging forehead) become more evident in the second year. By age 2, the ribs have widened and are oar-shaped. The [[liver]], [[spleen]] and [[heart]] are often enlarged. Children may experience noisy breathing and recurring upper respiratory tract and [[ear]] [[infection]]s. Feeding may be difficult for some children, and many experience periodic bowel problems. Children with Hurler syndrome often die before age 10 from obstructive airway disease, respiratory infections, or cardiac complications.  
Affected children may be quite large at [[childbirth|birth]] and appear normal but may have inguinal (in the groin) or umbilical (where the [[umbilical cord]] passes through the [[abdomen]]) hernias. Growth in height may be initially faster than normal, then begins to slow before the end of the first year and often ends around age 3. Many children develop a short body trunk and a maximum stature of less than 4 feet. Distinct facial features (including flat face, depressed nasal bridge, and bulging forehead) become more evident in the second year. By age 2, the ribs have widened and are oar-shaped. The [[liver]], [[spleen]] and [[heart]] are often enlarged. Children may experience noisy breathing and recurring upper respiratory tract and [[ear]] [[infection]]s. Feeding may be difficult for some children, and many experience periodic bowel problems. Children with Hurler syndrome often die before age 10 from obstructive airway disease, respiratory infections, or cardiac complications.  


Line 15: Line 15:
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs content]]
[[Category:Needs content]]
[[Category:Gastroenterology]]
[[Category:Genetic disorders]]
[[Category:Hepatology]]
[[Category:Syndromes]]
[[Category:Mature chapter]]
[[Category:Metabolic disorders]]
[[Category:Lysosomal storage diseases]]
[[Category:Cardiology]]
[[Category:Psychiatry]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Inborn errors of metabolism]]
[[Category: Needs overview]]

Revision as of 23:51, 25 February 2013

Hurler Syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hurler Syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Hurler syndrome history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hurler syndrome history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hurler syndrome history and symptoms

CDC on Hurler syndrome history and symptoms

Hurler syndrome history and symptoms in the news

Blogs on Hurler syndrome history and symptoms

Directions to Hospitals Treating Hurler syndrome

Risk calculators and risk factors for Hurler syndrome history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.

Overview

Affected children may be quite large at birth and appear normal but may have inguinal (in the groin) or umbilical (where the umbilical cord passes through the abdomen) hernias. Growth in height may be initially faster than normal, then begins to slow before the end of the first year and often ends around age 3. Many children develop a short body trunk and a maximum stature of less than 4 feet. Distinct facial features (including flat face, depressed nasal bridge, and bulging forehead) become more evident in the second year. By age 2, the ribs have widened and are oar-shaped. The liver, spleen and heart are often enlarged. Children may experience noisy breathing and recurring upper respiratory tract and ear infections. Feeding may be difficult for some children, and many experience periodic bowel problems. Children with Hurler syndrome often die before age 10 from obstructive airway disease, respiratory infections, or cardiac complications.

There is some clinical similarity with Hunter syndrome.


References