Gemeprost

Gemeprost

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Clinical data
Routes of administration	Pessary
ATC code	G02AD03 (WHO)
Identifiers
IUPAC name methyl (E)-7-[(1R,2S,3R)-3-hydroxy-2- [(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]- 5-oxo-cyclopentyl]hept-2-enoate
CAS Number	64318-79-2
PubChem CID	5282237
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C23H38O5
Molar mass	394.545 g/mol
3D model (JSmol)	Interactive image
SMILES CCCCC(C)(C)C(C=CC1C(CC(=O)C1CCCCC=CC(=O)OC)O)O

WikiDoc Resources for Gemeprost
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Evidence Based Medicine
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Healthcare Provider Resources
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Experimental / Informatics
List of terms related to Gemeprost

Gemeprost (16, 16-dimethyl-trans-delta2 PGE₁ methyl ester) is an analogue of prostaglandin E₁.

Clinical use

In pessary form as the second drug in medical abortion regimen in the UK and Sweden. Gemeprost softens and dilates the cervix and stimulates the uterus to contract.

Side effects

Vaginal bleeding, cramps, nausea, vomiting, loose stools or diarrhea, headache, muscle weakness; dizziness; flushing; chills; backache; dyspnoea; chest pain; palpitations and mild pyrexia. Rare: Uterine rupture, severe hypotension, coronary spasms with subsequent myocardial infarctions.

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