Sideroblastic anemia laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of sideroblastic anemia include decreased MCV, low reticulocyte count, increased ferritin levels, decreased total iron binding capacity. Hematocrit falls to 20-30%. Serum iron levels are high so as transferrin saturation. In sideroblastic anemia associated with lead toxicity, basophilic stippling of red blood cells on peripheral smear is common. Prussian Blue stain of RBC in marrow, shows ringed sideroblasts. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
* Microcytic hypochromic anemia | |||
* Normal to low reticulocyte count | |||
* Increased [[ferritin]] levels | * Increased [[ferritin]] levels | ||
* Decreased [[total iron-binding capacity]] | * Decreased [[total iron-binding capacity]] | ||
* [[Hematocrit]] | * [[Hematocrit]] , 20-30% | ||
* | * High serum Iron | ||
* High [[transferrin saturation]] | * High [[transferrin saturation]]. | ||
* Basophilic stippling of red blood cells on peripheral blood smear seen in [[lead poisoning]], | |||
* | * Prussian Blue stain of RBC in marrow, shows ringed sideroblasts. | ||
* | |||
==References== | ==References== | ||
Revision as of 17:31, 8 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory findings consistent with the diagnosis of sideroblastic anemia include decreased MCV, low reticulocyte count, increased ferritin levels, decreased total iron binding capacity. Hematocrit falls to 20-30%. Serum iron levels are high so as transferrin saturation. In sideroblastic anemia associated with lead toxicity, basophilic stippling of red blood cells on peripheral smear is common. Prussian Blue stain of RBC in marrow, shows ringed sideroblasts.
Laboratory Findings
- Microcytic hypochromic anemia
- Normal to low reticulocyte count
- Increased ferritin levels
- Decreased total iron-binding capacity
- Hematocrit , 20-30%
- High serum Iron
- High transferrin saturation.
- Basophilic stippling of red blood cells on peripheral blood smear seen in lead poisoning,
- Prussian Blue stain of RBC in marrow, shows ringed sideroblasts.