Sideroblastic anemia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Nazia Fuad M.D.
Overview
The hallmark of sideroblastic anemia is fatigue, decreased exercise tolerance, and dizziness. A positive history of toxin or drug exposure, family history of unexplained anemia, and alcoholism is suggestive of sideroblastic anemia. The most common symptoms of sideroblastic anemia include malaise, irritability, fatigue, dyspnea on exertion, and palpitations. Less common symptoms are diarrhea, polyuria, deafness, blindness, and abdominal pain.
History and Symptoms
- The hallmark of sideroblastic anemia is fatigue, decreased exercise tolerance, and dizziness.
- A positive history of toxin or drug exposure, family history of unexplained anemia, GI surgery, use of copper chelating agents, myelodysplastic syndrome, lead exposure, and alcoholism is suggestive of sideroblastic anemia. The most common symptoms of sideroblastic anemia include malaise, irritability, fatigue, dyspnea on exertion, and palpitation.
History
Patients with sideroblastic anemia may have a positive history of:[1]
- Alcohol use
- Medications
- Positive genetic history
- GI surgery
- Enteral or parenteral nutrition
- Increase zinc ingestion
- Use of copper chelating agents
- Malabsorption
- Myelodysplastic syndrome
- Lead exposure
- Psychiatric disease with possible coin ingestion
Common Symptoms
Common symptoms of sideroblastic anemia include:
- Headache
- Malaise
- Fatigue
- Dyspnea on exertion
- Palpitations
- Irritability
Less Common Symptoms
Less common symptoms of sideroblastic anemia include:
- Abdominal pain
- Incoordination
- Failure of growth
- Diarrhea
- Polyuria
- Blindness
- Deafness
References
References
- ↑ Bottomley SS, Fleming MD (August 2014). "Sideroblastic anemia: diagnosis and management". Hematol. Oncol. Clin. North Am. 28 (4): 653–70, v. doi:10.1016/j.hoc.2014.04.008. PMID 25064706.