Whipple's disease medical therapy: Difference between revisions

Jump to navigation Jump to search
Line 15: Line 15:
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
*Maintenance therapy
*Maintenance therapy
**Preferred regimen (1): Trimethoprim-sulfamethoxazole one DS tablet PO q12h
**Preferred regimen (1): [[Sulfamethoxazole-Trimethoprim|Trimethoprim-sulfamethoxazole]] one DS tablet PO q12h
**Alternative regimen (1): Doxycycline 100 mg PO q12h AND Hydroxychloroquine 200 mg PO q8h
**Alternative regimen (1): [[Doxycycline]] 100 mg PO q12h <u>'''AND'''</u> [[Hydroxychloroquine]] 200 mg PO q8h


==== CNS infection ====
==== CNS infection ====
Line 24: Line 24:
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
*Maintenance therapy
*Maintenance therapy
**Preferred regimen (1):     
**Preferred regimen (1): [[Sulfamethoxazole-Trimethoprim|Trimethoprim-sulfamethoxazole]] one DS tablet PO q12h    
**Alternative regimen (1):
**Alternative regimen (1): [[Doxycycline]] 100 mg PO q12h '''<u>AND</u>''' [[Hydroxychloroquine]] 200 mg PO q8h


==== Endocarditis ====
==== Endocarditis ====
Line 33: Line 33:
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
**Alternative regimen (1): [[Meropenem]] 1 g IV q8h for 14 days   
*Maintenance therapy
*Maintenance therapy
**Preferred regimen (1):     
**Preferred regimen (1): [[Sulfamethoxazole-Trimethoprim|Trimethoprim-sulfamethoxazole]] one DS tablet PO q12h    
**Alternative regimen (1):
**Alternative regimen (1): [[Doxycycline]] 100 mg PO q12h '''<u>AND</u>''' [[Hydroxychloroquine]] 200 mg PO q8h


==== Relapse ====
==== Relapse ====

Revision as of 21:11, 2 November 2017

Whipple's disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Whipple's disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Whipple's disease medical therapy On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Whipple's disease medical therapy

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Whipple's disease medical therapy

CDC on Whipple's disease medical therapy

Whipple's disease medical therapy in the news

Blogs on Whipple's disease medical therapy

Directions to Hospitals Treating Whipple's disease

Risk calculators and risk factors for Whipple's disease medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

The mainstay of treatment for Whipple's disease is systemic long-term antibiotic therapy. Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].

Medical Therapy

  • Pharmacologic medical therapy for Whipple's disease includes long-term antibiotics.

Classic Whipple's disease

CNS infection

Endocarditis

Relapse

  • Initial therapy
    • Preferred regimen (1): Ceftriaxone 2 g IV qd for 14 days
    • Preferred regimen (2): Penicillin G 2 million units IV q4h for 14 days
    • Alternative regimen (1): Meropenem 1 g IV q8h for 14 days
  • Maintenance therapy
    • Preferred regimen (1):
    • Alternative regimen (1):

References


Template:WS Template:WH