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==Overview==
 
==Differentiating Parotitis from Other Diseases==
Parotitis must be differentiated from the following diseases:
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
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! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Disease}}
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|Findings}}
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| style="padding: 5px 5px; background: #DCDCDC;" |'''[[Retropharyngeal abscess]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with [[neck pain]], [[stiff neck]], [[torticollis]] and may include enlarged [[cervical]] [[lymph nodes]], [[fever]], [[malaise]], [[stridor]], and barking [[cough]]. Requires [[tonsillectomy]] and use of [[antibiotics]].<ref name="pmid12777558">{{cite journal |vauthors=Craig FW, Schunk JE |title=Retropharyngeal abscess in children: clinical presentation, utility of imaging, and current management |journal=Pediatrics |volume=111 |issue=6 Pt 1 |pages=1394–8 |year=2003 |pmid=12777558 |doi= |url=}}</ref>
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Angioneurotic edema]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with [[swelling]] of the [[dermis]], [[subcutaneous]], [[mucosa]] and [[submucosal]] tissues. Can occur in the [[upper respiratory]] system and result in [[stridor]] and [[respiratory arrest]], requiring emergency treatment. Acquired [[angioneurotic edema]] results from an [[allergic]] reaction and be treated with [[epinephrine]].<ref name="pmid20667117">{{cite journal |vauthors=Cicardi M, Zanichelli A |title=Acquired angioedema |journal=Allergy Asthma Clin Immunol |volume=6 |issue=1 |pages=14 |year=2010 |pmid=20667117 |pmc=2925362 |doi=10.1186/1710-1492-6-14 |url=}}</ref>
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Typhoid fever]]'''
| style="padding: 5px 5px; background: #F5F5F5;" | Presents with [[fever]], [[headache]], [[rash]], gastrointestinal symptoms, with [[lymphadenopathy]], relative [[bradycardia]], [[cough]] and [[leucopenia]] and sometimes [[sore throat]]. [[Blood]] and [[stool culture]] can confirm the presence of the causative bacteria.
|-
| style="padding: 5px 5px; background: #DCDCDC;" |'''[[Malaria]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with acute [[fever]], [[headache]] and sometimes [[diarrhea]] (children). A [[blood smear]]s must be examined for malaria parasites. The presence of [[parasites]] does not exclude a concurrent viral infection. An [[antimalarial]] should be prescribed as an [[empiric therapy]].
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Lassa fever]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Disease onset is usually gradual, with [[fever]], [[sore throat]], [[cough]], [[pharyngitis]], and [[facial edema]] in the later stages. [[Inflammation]] and exudation of the [[pharynx]] and [[conjunctiva]] are common.
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Yellow fever]] and other [[Flaviviridae]] '''
| style="padding: 5px 5px; background: #F5F5F5;" | Present with [[hemorrhage|hemorrhagic]] complications. [[Epidemiological]] investigation may reveal a pattern of disease [[transmission]] by an insect vector. Virus isolation and serological investigation serves to distinguish these [[viruses]]. Confirmed history of previous [[yellow fever]] [[vaccination]] will rule out [[yellow fever]].
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| style="padding: 5px 5px; background: #DCDCDC;" | '''Others'''
| style="padding: 5px 5px; background: #F5F5F5;" |[[Viral hepatitis]], [[leptospirosis]], [[rheumatic fever]], [[typhus]], and [[mononucleosis]] can produce [[signs]] and [[symptoms]] that may be confused with [[Ebola]] in the early stages of [[infection]].
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==References==
==References==
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Revision as of 17:55, 7 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Differentiating Parotitis from Other Diseases

Parotitis must be differentiated from the following diseases:

Disease Findings
Retropharyngeal abscess Presents with neck pain, stiff neck, torticollis and may include enlarged cervical lymph nodes, fever, malaise, stridor, and barking cough. Requires tonsillectomy and use of antibiotics.[1]
Angioneurotic edema Presents with swelling of the dermis, subcutaneous, mucosa and submucosal tissues. Can occur in the upper respiratory system and result in stridor and respiratory arrest, requiring emergency treatment. Acquired angioneurotic edema results from an allergic reaction and be treated with epinephrine.[2]
Typhoid fever Presents with fever, headache, rash, gastrointestinal symptoms, with lymphadenopathy, relative bradycardia, cough and leucopenia and sometimes sore throat. Blood and stool culture can confirm the presence of the causative bacteria.
Malaria Presents with acute fever, headache and sometimes diarrhea (children). A blood smears must be examined for malaria parasites. The presence of parasites does not exclude a concurrent viral infection. An antimalarial should be prescribed as an empiric therapy.
Lassa fever Disease onset is usually gradual, with fever, sore throat, cough, pharyngitis, and facial edema in the later stages. Inflammation and exudation of the pharynx and conjunctiva are common.
Yellow fever and other Flaviviridae Present with hemorrhagic complications. Epidemiological investigation may reveal a pattern of disease transmission by an insect vector. Virus isolation and serological investigation serves to distinguish these viruses. Confirmed history of previous yellow fever vaccination will rule out yellow fever.
Others Viral hepatitis, leptospirosis, rheumatic fever, typhus, and mononucleosis can produce signs and symptoms that may be confused with Ebola in the early stages of infection.

References

  1. Craig FW, Schunk JE (2003). "Retropharyngeal abscess in children: clinical presentation, utility of imaging, and current management". Pediatrics. 111 (6 Pt 1): 1394–8. PMID 12777558.
  2. Cicardi M, Zanichelli A (2010). "Acquired angioedema". Allergy Asthma Clin Immunol. 6 (1): 14. doi:10.1186/1710-1492-6-14. PMC 2925362. PMID 20667117.

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