Retinoblastoma history and symptoms: Difference between revisions
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In taking a medical history, the doctor will ask questions about present illness, a family history of retinoblastoma or risk factors for retinoblastoma and signs and symptoms that may suggest retinoblastoma. The physician must specifically inquire about a family history of eye tumors, blindness, childhood malignancies, or enucleations. A family history of other cancers such as sarcomas should also be inquired. The parents should be asked if either strabismus and/or leukocoria have been observed. <ref name="CCS"> Retinoblastoma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/retinoblastoma/diagnosis/?region=onAccessed on October 10 2015</ref> | In taking a medical history, the doctor will ask questions about present illness, a family history of retinoblastoma or risk factors for retinoblastoma and signs and symptoms that may suggest retinoblastoma. The physician must specifically inquire about a family history of eye tumors, blindness, childhood malignancies, or enucleations. A family history of other cancers such as sarcomas should also be inquired. The parents should be asked if either strabismus and/or leukocoria have been observed. <ref name="CCS"> Retinoblastoma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/retinoblastoma/diagnosis/?region=onAccessed on October 10 2015</ref> | ||
==Symptoms== | ==Symptoms== | ||
The most common finding of retinoblastoma is | The most common finding of retinoblastoma is leukocoria which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex.<ref name="pmid14654593">{{cite journal| author=Abramson DH, Beaverson K, Sangani P, Vora RA, Lee TC, Hochberg HM et al.| title=Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival. | journal=Pediatrics | year= 2003 | volume= 112 | issue= 6 Pt 1 | pages= 1248-55 | pmid=14654593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14654593 }} </ref><ref name="pmid3746592">{{cite journal| author=Abramson DH, Ellsworth RM, Grumbach N, Sturgis-Buckhout L, Haik BG| title=Retinoblastoma: correlation between age at diagnosis and survival. | journal=J Pediatr Ophthalmol Strabismus | year= 1986 | volume= 23 | issue= 4 | pages= 174-7 | pmid=3746592 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3746592 }} </ref> Some children with retinoblastoma can develop a strabismus, nystagmus, red eye and squint which is commonly referred to as "cross-eyed" or "wall-eyed" (strabismus). Emergency referral to an Opthalmologist is warranted when a child presents with Leukocoria or Strabismus.<ref name="NIH"> Retinoblastoma. National Cancer Institute(2015) http://www.cancer.gov/types/retinoblastoma/hp/retinoblastoma-treatment-pdq#link/_718_toc Accessed on October 10 2015</ref> | ||
Less common symptoms of retinoblastoma include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma Accessed on October 10 2015</ref> | Less common symptoms of retinoblastoma include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma Accessed on October 10 2015</ref> |
Revision as of 01:45, 15 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
The hallmark of retinoblastoma is leukocoria which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex. A positive family history of retinoblastoma may be present. Less common symptoms of retinoblastoma include deterioration of vision, a red and irritated eye, eye pain, squint, proptosis and fever.
History
In taking a medical history, the doctor will ask questions about present illness, a family history of retinoblastoma or risk factors for retinoblastoma and signs and symptoms that may suggest retinoblastoma. The physician must specifically inquire about a family history of eye tumors, blindness, childhood malignancies, or enucleations. A family history of other cancers such as sarcomas should also be inquired. The parents should be asked if either strabismus and/or leukocoria have been observed. [1]
Symptoms
The most common finding of retinoblastoma is leukocoria which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex.[2][3] Some children with retinoblastoma can develop a strabismus, nystagmus, red eye and squint which is commonly referred to as "cross-eyed" or "wall-eyed" (strabismus). Emergency referral to an Opthalmologist is warranted when a child presents with Leukocoria or Strabismus.[4]
Less common symptoms of retinoblastoma include:[5]
- Deterioration of vision
- Proptosis
- Eye pain
- Squint
- Fever
- Symptoms of glaucoma which include:
- Severe headache
- Nausea and vomiting
- Blurred vision
- Halos around lights
References
- ↑ Retinoblastoma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/retinoblastoma/diagnosis/?region=onAccessed on October 10 2015
- ↑ Abramson DH, Beaverson K, Sangani P, Vora RA, Lee TC, Hochberg HM; et al. (2003). "Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival". Pediatrics. 112 (6 Pt 1): 1248–55. PMID 14654593.
- ↑ Abramson DH, Ellsworth RM, Grumbach N, Sturgis-Buckhout L, Haik BG (1986). "Retinoblastoma: correlation between age at diagnosis and survival". J Pediatr Ophthalmol Strabismus. 23 (4): 174–7. PMID 3746592.
- ↑ Retinoblastoma. National Cancer Institute(2015) http://www.cancer.gov/types/retinoblastoma/hp/retinoblastoma-treatment-pdq#link/_718_toc Accessed on October 10 2015
- ↑ Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma Accessed on October 10 2015