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====Alveolar Rhabdomyosarcoma====
====Alveolar Rhabdomyosarcoma====
Characterized by Alveolus-like pattern:
Characterized by Alveolus-like pattern:
*Fibrous septae lined by tumor cells.
*Fibrous [[septae]] lined by tumor cells.
**Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space.
**Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space.
**Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma.
**Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma.
Rhabdomyoblasts: Essentially diagnostic cells with [[Eccentric nucleus]] and Moderate amount of intensely [[eosinophilic cytoplasm]].
Rhabdomyoblasts: Essentially diagnostic cells with [[Nucleus|eccentric nucleus]] and Moderate amount of intensely eosinophilic cytoplasm.


==References==
==References==

Revision as of 14:54, 1 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pathophysiology

Microscopic Pathology

Characteristic features on microscopic analysis are variable depending on the chondrosarcoma subtype:

Alveolar Rhabdomyosarcoma

Characterized by Alveolus-like pattern:

  • Fibrous septae lined by tumor cells.
    • Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space.
    • Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma.

Rhabdomyoblasts: Essentially diagnostic cells with eccentric nucleus and Moderate amount of intensely eosinophilic cytoplasm.

References

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