Griseofulvin indications and usage: Difference between revisions

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==Description==
==Indications and Usage==


Griseofulvin is an antibiotic derived from a species of Penicillium. Each GRIFULVIN V® (griseofulvin tablets) microsize Tablet contains either 250mg or 500mg of griseofulvin microsize, and also contains calcium stearate, colloidal silicon dioxide, starch, and wheat gluten. Additionally, the 250 mg tablet also contains dibasic calcium phosphate.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = GRIFULVIN V (GRISEOFULVIN) TABLET [ORTHO-MCNEIL PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b876327f-d496-46a7-ae39-011baaad6aa7 | publisher =  | date =  | accessdate =  }}</ref>
Major indications for GRIFULVIN V® (griseofulvin tablets) microsize are:
 
*'''[[Tinea capitis]]''' (ringworm of the scalp)
 
*'''[[Tinea corporis]]''' (ringworm of the body)
 
*'''[[Tinea pedis]]''' (athlete's foot)
 
*'''[[Tinea unguium]]''' (onychomycosis; ringworm of the nails)
 
*'''[[Tinea cruris]]''' (ringworm of the thigh)
 
*'''[[Tinea barbae]]''' (barber's itch)
 
GRIFULVIN V® (griseofulvin tablets) microsize '''inhibits''' the growth of those genera of fungi that '''commonly cause ringworm infections of the hair, skin, and nails''', such as:
 
*'''[[Trichophyton rubrum]]'''
*'''Trichophyton tonsurans'''
 
*'''Trichophyton mentagrophytes'''
 
*'''Trichophyton interdigitalis'''
 
*'''Trichophyton verrucosum'''
 
*'''Trichophyton sulphureum'''
 
*'''Trichophyton schoenleini'''
 
*'''Microsporum audouini'''
 
*'''[[Microsporum]] canis'''
 
*'''Microsporum gypseum'''
 
*'''Epidermophyton floccosum'''
 
*'''Trichophyton megnini'''
 
*'''Trichophyton gallinae'''
 
*'''Trichophyton crateriform'''
 
'''Note''': Prior to therapy, the type of fungi responsible for the infection should be identified. The use of the drug is not justified in minor or trivial infections which will respond to topical antifungal agents alone.
 
It is '''not effective''' in<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = GRIFULVIN V (GRISEOFULVIN) TABLET [ORTHO-MCNEIL PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b876327f-d496-46a7-ae39-011baaad6aa7 | publisher =  | date =  | accessdate =  }}</ref>:
 
*'''[[Bacterial infections]]'''
 
*'''[[Candidiasis]]''' (Moniliasis)
 
*'''[[Histoplasmosis]]'''
 
*'''[[Actinomycosis]]'''
 
*'''[[Sporotrichosis]]'''
 
*'''[[Chromoblastomycosis]]'''
 
*'''[[Coccidioidomycosis]]'''
 
*'''[[North American Blastomycosis]]'''
 
*'''[[Cryptococcosis]]''' (Torulosis)
 
*'''[[Tinea versicolor]]'''
 
*'''[[Nocardiosis]]'''


==References==
==References==

Latest revision as of 23:09, 5 January 2014

Griseofulvin
Grifulvin V®,GRIS-PEG® Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Indications and Usage

Major indications for GRIFULVIN V® (griseofulvin tablets) microsize are:

GRIFULVIN V® (griseofulvin tablets) microsize inhibits the growth of those genera of fungi that commonly cause ringworm infections of the hair, skin, and nails, such as:

  • Trichophyton tonsurans
  • Trichophyton mentagrophytes
  • Trichophyton interdigitalis
  • Trichophyton verrucosum
  • Trichophyton sulphureum
  • Trichophyton schoenleini
  • Microsporum audouini
  • Microsporum gypseum
  • Epidermophyton floccosum
  • Trichophyton megnini
  • Trichophyton gallinae
  • Trichophyton crateriform

Note: Prior to therapy, the type of fungi responsible for the infection should be identified. The use of the drug is not justified in minor or trivial infections which will respond to topical antifungal agents alone.

It is not effective in[1]:

References

  1. "GRIFULVIN V (GRISEOFULVIN) TABLET [ORTHO-MCNEIL PHARMACEUTICALS]".

Adapted from the FDA Package Insert.